Background Acinetobacter infections, especially multidrug-resistant (MDR) Acinetobacter infections, are a global health problem. This study aimed to describe clinical outcomes in patients with confirmed Acinetobacter spp. isolates who were treated with tigecycline in randomized clinical trials. Materials and methods Data from 14 multinational, randomized (open-label or double-blind), and acti...

| May 2014 | 480 comparable with a report from USA that showed 46% of isolates were resistant to all of conventional antibiotics.[3] Totally, 66 isolates (95.65%) were carbapenem-resistant. In the six patients, Acinetobacter was isolated from multiple sites or one site for several times. It should be mentioned that all of six patients were infected or colonized with XDR strains, died during our...

BACKGROUND The alarming spread of antibiotic-resistant bacteria causing healthcare-associated infections has been extensively reported in recent medical literature. AIMS To compare trends in antimicrobial consumption and development of resistance among isolates of Acinetobacter spp. and Pseudomonas aeruginosa that cause hospital infections. STUDY DESIGN Cross-sectional study. METHODS A st...

BACKGROUND There has been an increase in worldwide infections caused by carbapenem-resistant Acinetobacter. This poses a therapeutic challenge as few treatment options are available. OBJECTIVES The aim of this study was to evaluate the efficacy and safety of polymyxins and ampicillin/sulbactam for treating infections caused by carbapenem-resistant Acinetobacter spp. and to evaluate prognostic...

15 Production of OXA-23 carbapenemase is the most common reason for the increasing 16 carbapenem resistance in Acinetobacter spp. This study was conducted to reveal the genetic 17 basis of the blaOXA-23 dissemination in Acinetobacter spp. in China. A total of sixty-three 18 carbapenem-resistant OXA-23-producing Acinetobacter spp. isolates, representing different 19 backgrounds, were selected fr...

Objective: The emergence of infections by Acinetobacter spp causes serious threats and further limits the treatment options. The present study aims to determine prevalence of ESBL and MBL among Acinetobacter species. Materials and methods: Various clinical specimens and isolates were identified using a standard bacteriological protocol. Antimicrobial sensitivity patterns were determined using K...

As a first national surveillance of Acinetobacter in Cuba, a total of 500 Acinetobacter spp. isolates recovered from 30 hospitals between 2010 and 2012 were studied. Acinetobacter baumannii-calcoaceticus complex accounted for 96.4% of all the Acinetobacter isolates, while other species were detected at low frequency (A. junii 1.6%, A. lwoffii 1%, A. haemolyticus 0.8%, A. soli 0.2%). Resistance ...

Background and Objective: Aerobic nonfermenting gram-negative bacilli (non-fermenters) are now emerging as important uropathogens. This study was done to know the prevalence of non-fermenters in Urinary Tract Infections (UTI) along with their antibiotic sensitivity. Method: 5436 mid stream urine specimens received in six months period from July to December 2007 were subjected to Gram,s staining...

Clinical infections caused by Acinetobacter spp. have increasing public health concerns because of their global occurrence and ability to acquire multidrug resistance. Acinetobacter calcoaceti-cus–Acinetobacter baumannii (ACB) complex encompasses A. calcoa-ceticus, A. baumannii, A. pittii (formerly genomic species 3), and A nosocomial (formerly genomic species 13TU), which are predominantly res...

In this study, urinary catheter utilization rates, the causative agents for catheter-associated urinary tract infection (CAUTI) and their antimicrobial susceptibilities in intensive care units (ICUs) in 2009 were investigated at Gazi university hospital. We aimed to determine the causative agents and risk factors for CAUTIs, and antimicrobial susceptibilities of the pathogens; and also sensitiv...