Anthracycline antibiotics aclacinomycins (ACMs) are aklavinone glycosides with variation in the trisaccharide moiety and were produced by Streptomyces galilaeus MA144-M1. Their production" and structural elucidation') were previously reported. By the isolation of various mutants') and the conversion of hypothetical precursors fed in the cultural medium'), we found that ACMs were formed by a ste...

New single crystals of R2PdIn8 (R = Pr, Ce) and R2RhIn8 compounds have been synthesized by solution growth from In flux and studied with respect to structure and electronic properties. Pr2RhIn8 exhibits van Vleck paramagnetism and strong magnetocrystalline anisotropy attributed to a crystal-field effect on the Pr ion. Ce2PdIn8 compound is paramagnetic down to 0.7 K, superconductivity below 0.7 ...

Benchmarking is an important phase in developing any new software technique because it helps to validate the underlying theory in the specific problem domain. But benchmarking of new software strategies is a very complex problem, because it is difficult (if not impossible) to test, validate and verify the results of the various schemes in completely different settings. This is even more true in...

This thesis presents the design and testing of asynchronous communication mechanism (ACM) circuits, and the development of an asynchronous circuit synthesis method which not only supports the ACM work but also has much wider application potential. ACMs are a unique approach to data transmission between subsystems not synchronized with one another. The successful systematic implementation of ACM...

Earth observation satellite imagery is increasingly accessible, and has become a key component for vegetation mapping monitoring. Sentinel-2 satellites acquire optical images with five days’ revisit frequency, which an important feature to increase the probability of acquisition reasonable cloud cover in tropical regions. Regular reliable observations open perspectives monitoring properties bio...

INTRODUCTION Despite the frequency of acute asthma in the emergency department (ED) and the availability of guidelines, significant practice variation exists. Asthma care maps (ACMs) may standardize treatment. This study examined the use of an ACM to determine its effects on patient management in a regional hospital. METHODS Patients aged 2 to 65 years who presented to the ED with a primary d...

ZLOTXICK T HE associatiomi of hypem'globulimseniia with ams imscm'ease imi the msunsber of boise marrow plasmna cells is a well-kmsowmi phenomemion. Bing & Plum' first drew attenstioms to this amid noted that " a comparison of the various affectiomss in w'hsichi hsyperglobunlinsemssia is found, shows as a comnmon feature ais augmeustatious of the plasmusa cells amid other cells belomsginsg to t...

α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) and αaminomuconate-ε-semialdehyde dehydrogenase (AMSDH) are two neighboring enzymes in the L-tryptophan and 2-nitrobenzoic acid degradation pathways. The substrates of the two enzymes, α-amino-β-carboxymuconate-ε-semialdehyde (ACMS) and α-aminomuconate-ε-semialdehyde (2-AMS), are unstable and spontaneously decay to quinolinic acid a...

1 Abstract The cornerstone software component of high-end production systems is a database management system. Digital has successfully ported the DEC Rdb for OpenVMS relational database management system and the DEC DBMS for OpenVMS network database management system to the Alpha AXP platform. Rdb and DBMS were perhaps the most complex layered products to be ported. The tight coupling of these ...

The full functional role of RNA in all domains of life is yet to be explored. Deep sequencing technologies generate massive data about RNA transcripts with functional potential. To decipher this information, bioinformatics methods for structural analysis are in demand. With this thesis at hand, we want to improve current secondary structure prediction in different respects. The introductory cha...