background: the present study aimed to determine the prevalence and associated risk factors of vaginal trichomoniasis in women referred to gynecologic clinic in benha university hospital, egypt. methods: two hundred female patients enrolled in the study. vaginal samples were obtained from them and examined for t. vaginalis by wet mount, giemsa stain, acridine orange (ao) stain and culture on mo...

course similar to that of the other tissues during the first 8-10 days, but after that time until the premortal stage a residue persists which gives the Roe & Kuether reaction and which reduces indophenol. 5. Scurvy develops in guinea-pigs when the curve of the ascorbic acid tissue concentration reaches asymptotic values for long periods of depletion, and there is no definite correlation betwee...

In this work, the acridine nucleus was used as a lead-compound for structural modification by adding different substituted thiosemicarbazide moieties. Eight new (Z)-2-(acridin-9-ylmethylene)-N-phenylhydrazinecarbothioamide derivatives (3a-h) were synthesized, their antiproliferative activities were evaluated, and DNA binding properties were performed with calf thymus DNA (ctDNA) by electronic a...

In this study, some pyrazolone-based Schiff base derivatives 2a-e (except 2a) were synthesized for the first time and structurally illuminated by spectroscopic techniques (1H, 13C NMR, FT-IR) elemental analysis. All molecules screened their anticancer antioxidant activities, as well AChE, BChE, tyrosinase inhibitory properties. The obtained results exhibited that compounds 1b (IC50 = 9.497 μΜ) ...

Optical absorption and fluorescence emission spectral studies of acridine in different solvents namely, carbon tetrachloride, dichloromethane, propan-2-ol, ethanol, methanol, acetonitrile, and N,Ndimenthyl formamide have been investigated. Oscillator strength and transition dipole moment of the acridine have been elucidated from the optical absorption measurement. The ratio of the excited state...

The title compound, C(28)H(28)N(2)O(5), consists of a partially hydrogenated acridine ring system with two substituted phenyl substituents on the dihydro-pyridine ring which are both nearly perpendicular to the mean plane of the acridine unit [dihedral angles of 81.3 (1) and 89.6 (1)° between the central ring of acridine and the methoxyphenyl and nitrophenyl rings, respectively]. The dihydro-py...

Bis-acridine orange peptides carrying two acridine oranges at the epsilon-amino moieties of both terminal lysines of a tetra(lysine) chain showed a ca. 200-fold fluorescence enhancement upon addition of double stranded DNA.