The present work is an attempt to model, analyze, and control the flow at the base of an abruptly expanded circular duct by using design of experiments (DOE) and response surface methodology (RSM). Tiny-jets in the form of orifice were positioned at an interval of 900, 6.5 mm from the primary axis of the main jet of the nozzle. Experiments were conducted to measure two responses namely, base pr...

background: production of tissue plasminogen activator protein (t-pa) in prokaryotes systems has many problems such as the lack of active protein production, multiple purification steps, and renaturation process which has been shown to be costly and time-consuming. methods: in this study, reteplase which is the nonglycosylated active domain of t-pa was used to transform top10 escherichia coli (...

Magnetorheological elastomer (MRE) base isolator is a new semi-active control device that has recently acquired more attention. This paper proposes a new model for MRE base isolator to portray the nonlinear hysteresis between generated force and the displacement. In this model, a hyperbolic expression is proposed to compare with the classical Bouc-Wen model, which includes internal dynamics rep...

Bears are iconic mammals with a complex evolutionary history. Natural bear hybrids and studies of few nuclear genes indicate that gene flow among bears may be more common than expected and not limited to polar and brown bears. Here we present a genome analysis of the bear family with representatives of all living species. Phylogenomic analyses of 869 mega base pairs divided into 18,621 genome f...

TrmA catalyzes S-adenosylmethionine (AdoMet)-dependent methylation of U54 in most tRNAs. We solved the structure of the Escherichia coli 5-methyluridine (m(5)U) 54 tRNA methyltransferase (MTase) TrmA in a covalent complex with a 19-nt T arm analog to 2.4-A resolution. Mutation of the TrmA catalytic base Glu-358 to Gln arrested catalysis and allowed isolation of the covalent TrmA-RNA complex for...

The goals of this project are to develop rehabilitation strategies and enhance seismic design guidelines for key equipments in power substations, which are one of the most critical facilities in a power system. Furthermore, it will provide the knowledge base to be integrated into the overall loss estimation model for the entire power network. To achieve these goals, key substation equipments ar...