background : coronary artery diseases are one of the causes of early death all over the world. in developed countries, ischemic heart disease is responsible for the half of the entire mortalities; however in developing countries it is estimated from 9 million deaths per year annually 32 percent of all deaths due to coronary artery disease. acute coronary syndromes are responsible for over 250,0...

The development of coronary atherosclerosis in response to acute intimal injury and severe hypercholesterolemia was studied in 18 swine, nine normal and nine with von Willebrand's disease, an inherited disorder affecting platelet-vessel wall interactions. The left anterior descending coronary artery was denuded of endothelium by balloon catheterization, while the circumflex and right coronary a...

Takotsubo cardiomyopathy is a disorder characterized by left ventricular apical ballooning and electrocardiographic changes in the absence of coronary artery disease. While reversible in many cases, the mechanism of this disorder remains unclear. The most frequent clinical symptoms of takotsubo cardiomyopathy on admission are chest pain and dyspnea, resembling acute myocardial infarction. Here,...

Background: Nowadays, cardiovascular diseases (CVDs) are among the most common causes of mortalities worldwide. Parathyroid hormone (PTH) has an important role in the pathogenesis of CVDs. The aim of the current study was to compare serum PTH levels between patients with acute myocardial infarction (MI), unstable angina, and normal coronary function. Methods: This descriptive and analytic stud...

Acute coronary artery syndrome in the leading cause of morbidity and mortality in Western countries, and its epidemiological burden is also constantly increasing worldwide, including Asia. Due to social and economic consequences, a number of experimental and epidemiological studies have analyzed its etiology so far, in order to develop effective preventive and treatment measures. Thanks to thes...

Contrast induced nephropathy (CIN) is an important and well‐known complication in pa‐ tients with chronic renal insufficiency undergoing both coronary angiography and coronary interventions. The estimated incidence of CN after coronary angiography was around 15%. In fact, CIN is the third leading cause of acute renal failure in hospitalized patients [1]. CIN is usually transient disorder, but i...

Technetium-99m-pyrophosphate (99mTc-PYP) has been used, in combination with thallium-201, to estimate the site and extent of myocardial infarcts. We report a case of acute myocardial infarction with severe coronary disease in which the distribution of 99mTc-PYP was extensive. A 78-year-old man presented with dyspnea, and a diagnosis of non-ST-segment elevation acute myocar...

The occurrence of left bundle branch block (LBBB) is quite common in clinical practice. The changes in cardiac repolarization, caused by this disorder of electric conduction, may mask the presence of an acute myocardial infarction (AMI), delaying the diagnostic-therapeutic iter, with an important impact on prognosis. We describe the case of a woman of 59 years with LBBB, came to our observation...

INTRODUCTION Vasospastic angina (VSA) is an important functional cardiac disorder that leads to transient myocardial ischemia and is caused by sudden, intense and reversible coronary artery spasm resulting in subtotal or total occlusion. [1,2] VSA is associated with cardiac conditions such as stable or unstable angina, acute coronary syndromes and lethal arrhythmias. The patients usually presen...