BACKGROUND To compare the periodical incidence rates of genitourinary (GU) and gastrointestinal (GI) toxicity in patients who underwent prostate low-dose-rate brachytherapy between the monotherapy group (seed implantation alone) and the boost group (in combination with external beam radiation therapy (EBRT)). METHODS A total of 218 patients with a median follow-up of 42.5 months were enrolled...

Ruzu bitters black for men (RBBM) is a polyherbal product widely used amongst in Nigeria to enhance libido, rejuvenate male organs and manage erectile dysfunctions, prostate anomalies, weak erection, premature ejaculation. This study was carried out investigate the toxicological effect from use of herbal product. Acute toxicity test RBBM on rats two phases; 10 mg/kg, 100 mg/kg 1000 phase I 1600...

CONTEXT Previous reports of acute toxicity/harm associated with mephedrone use have been based on self-reported mephedrone use; toxicological screening has not been undertaken in these cases to determine whether mephedrone has been used. OBJECTIVE To report the first case series of analytically confirmed mephedrone-related acute toxicity. MATERIALS AND METHODS Serum samples were collected f...

PURPOSE To estimate the incidence of acute and late lower gastrointestinal tract toxicity (LGIT) in patients treated with 3D conformal radiotherapy (3DCRT) for localized prostate cancer (PC) and estimate the influence of dosimetric parameters and other possible factors. METHODS Ninety-four patients with localized PC treated with 3DCRT, with an estimated risk of lymph node involvement ?15%, ac...