نتایج جستجو برای: adam moulton

تعداد نتایج: 7372  

Journal: :Nature 1897

2005
Harvey S. James Adam Smith

There are two competing approaches sustainability in agriculture. One stresses a strict economic approach in which market forces should be allowed to guide the activities of agricultural producers. The other advocates the need to balance economic with environmental and social objectives, even to the point of reducing profitability. This paper shows how the writings of the 18 century moral philo...

2013
Zhen Guo Xunbo Jin Haiyan Jia

BACKGROUND Our study is to research the effect of inhibited ADAM-17 expression through the Notch pathway in renal carcinoma. METHODS Immunohistochemistry and western blot were used to examine the expression of ADAM-17 protein in renal cancer tissues. Proliferation and cell invasion of 786-o cells, as well as OS-RC-2 cells, after treatment with two different inhibitors of the Notch pathway, we...

Journal: :CoRR 2017
Zijun Zhang Lin Ma Zongpeng Li Chuan Wu

Optimization algorithms for training deep models not only affects the convergence rate and stability of the training process, but are also highly related to the generalization performance of the models. While adaptive algorithms, such as Adam and RMSprop, have shown better optimization performance than stochastic gradient descent (SGD) in many scenarios, they often lead to worse generalization ...

Journal: :Computational Linguistics 2015

Journal: :Current Biology 2011

Journal: :The Journal of Laryngology, Rhinology, and Otology 1920

Journal: :Psychiatric Bulletin 1994

Journal: :The Journal of Cell Biology 2000
Kousuke Iba Reidar Albrechtsen Brent Gilpin Camilla Fröhlich Frosty Loechel Anna Zolkiewska Kazuhiro Ishiguro Tetsuhito Kojima Wei Liu J. Kevin Langford Ralph D. Sanderson Cord Brakebusch Reinhard Fässler Ulla M. Wewer

The ADAMs (a disintegrin and metalloprotease) family of proteins is involved in a variety of cellular interactions, including cell adhesion and ecto- domain shedding. Here we show that ADAM 12 binds to cell surface syndecans. Three forms of recombinant ADAM 12 were used in these experiments: the cys-teine-rich domain made in Escherichia coli (rADAM 12-cys), the disintegrin-like and cysteine-ric...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2009
Michael J Duffy Eadaoin McKiernan Norma O'Donovan Patricia M McGowan

The ADAMs (a disintegrin and metalloproteinase) comprise a family of multidomain transmembrane and secreted proteins. One of their best-established roles is the release of biologically important ligands, such as tumor necrosis factor-alpha, epidermal growth factor, transforming growth factor-alpha, and amphiregulin. Because these ligands have been implicated in the formation and progression of ...

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