Most of the traditional medicinal plants in India are not scientifically validated. Scientific evaluation along with traditional knowledge is essential to obtain effective drugs for commercial purpose. Solena amplexicaulis belongs to the family, Cucurbitaceae, a traditional medicinal plant species of Tamil Nadu, India is being prescribed to cure various diseases. The present study is to establi...

A simple and reliable method of ultra-performance liquid chromatography with photodiode array detector (UPLC-PDA) was developed to control the quality of Radix Isatidis (dried root of Isatis indigotica) for chemical fingerprint analysis and quantitative analysis of eight bioactive constituents, including R,S-goitrin, progoitrin, epiprogoitrin, gluconapin, adenosine, uridine, guanosine, and hypo...

The value of milk on the open market is linked to its protein content, and standard methods for protein analysis rely on a simple nitrogen assay, with the protein concentration inferred from the nitrogen content. Consequently, the addition of chemicals rich in nitrogen, such as urea, can artificially increase the apparent protein content and thus the price demanded. Urea occurs naturally in mil...

To quantify methanol, a spurious adulterant in alcoholic beverages, attenuated total reflectance (ATR) technique is used. Synthetic samples (100) are prepared for developing a suitable calibration model. Spectra are recorded for all samples in wavelength region 4000-600 cm using Bio-Rad 175 C FTS spectrophotometer in ATR mode. Calibration equation is obtained using partial least squares (PLS) m...

Modified lycopodium spore method has been developed for simple and rapid quantification of herbal powdered formulations. Lycopodium spore method was performed on Panchsakar churna, an Ayurvedic formulation used in constipation and piles. Estimation of diagnostic characters of each ingredient of Panchsakar churna individually and collectively on the powdered formulation was carried out. Microsco...

Three new germacrane sesquiterpenes and a new m-menthane monoterpene were isolated together with four known compounds from the pericarp of Illicium lanceolatum, an adulterant to star anise (Illicium verum). All compounds were isolated from Illicium plants for the first time. The absolute stereochemistry of all germacranes and m-menthane was established by a combination of NMR and the modified M...

BACKGROUND Levamisole, a veterinary anti-helminthic, is a common adulterant in cocaine. Levamisole-induced vasculopathy (LIV) is a relatively new entity, and is being increasingly recognized since it was first reported in 2010. Although cutaneous findings, agranulocytosis, and positive antineutrophil cytoplasmic antibodies (ANCA) are characteristic, the full clinical picture and appropriate man...

Taraxacum formosanum (TF) is a medicinal plant used as an important component of health drinks in Taiwan. In this study, a rapid, sensitive and specific loop-mediated isothermal amplification (LAMP) assay for authenticating TF was established. A set of four specific LAMP primers was designed based on the nucleotide sequence of the internal transcribed spacer 2 (ITS2) nuclear ribosomal DNA (nrDN...

Maleic acid has been shown to be used as a food adulterant in the production of modified starch by the Taiwan Food and Drug Administration. Due to the potential toxicity of maleic acid to the kidneys, this study aimed to develop an analytical method to investigate the pharmacokinetics of maleic acid in rat blood and kidney cortex. Multiple microdialysis probes were simultaneously inserted into ...