UNLABELLED During the last decade there is a trend all over the world women at advanced age/older than 35 years old/ and especially educated ones to postpone their reproductive plans. Pregnancy and birth outcomes in women >35 years old I traditionally associated with increasing risk of complications both for the mother and the foetus. OBJECTIVE To study the frequency and the obstetric outcome...

BACKGROUND Advanced maternal age (AMA) is associated with several adverse pregnancy outcomes, hence these pregnancies are considered to be "high risk." A review of the empirical literature suggests that it is not clear how women of AMA evaluate their pregnancy risk. This study aimed to address this gap by exploring the risk perception of pregnant women of AMA. METHODS A qualitative descriptiv...

QUESTIONS UNDER STUDY To evaluate pregnancy outcome in pregnant women aged ≥45 years, termed very advanced maternal age (VAMA). METHODS We retrospectively compared the outcome of pregnancies in VAMA patients with controls aged 30 years at time of delivery. Subgroups of singleton and multiple pregnancies were also analysed. Incidences of maternal and fetal adverse outcomes were measured. Stati...

Objective: To explore the main risk factors of gestational diabetes mellitus in Wuhan, China. Methods: 206 women with gestational diabetes mellitus who were diagnosed in Hubei Maternal and Child Health Hospital between January 2014 and December 2015 were selected as case group. Meanwhile, 286 healthy pregnant women, who were delivered at the same time, were selected as control group. Maternal a...

Background: Congenital malformation (CM) is the major health problems in childhood because treatment and rehabilitation of children with CM is costly and complete recovery is usually impossible. For most of single primary defect the etiology is unknown. The aim of this study was to determine frequency of CM and its association with maternal age. Materials and Methods: This descriptive-observati...

It is widely acknowledged that age at marriage has a significant influence on fertility, particularly in countries where childbearing occurs within marriage. However, the complexities of this relationship are poorly understood, especially during fertility transitions. This paper investigates the complex relationship between marriage age and marital fertility by examining the initiation of child...

background: the discovery of circulating fetal dna in maternal blood led to the discovery of new strategies to perform noninvasive testing for prenatal diagnosis. objective: the purpose of the study was to detect fetal aneuploidy at chromosomes 13, 18, 21, x, and y by analysis of fetal cell-free dna from maternal blood, without endangering pregnancy. materials and methods: this retrospective st...

Parental ages are increasing in the developed world, and postponed parenthood may have a negative association with the cognitive ability of offspring. There is, however, inconclusive evidence regarding the impact of both maternal and paternal ages. We have been able to reduce or eliminate unobserved confounding by using methods that account for fixed parental characteristics shared by brothers....