Promising new hallmarks of cancer is alteration of energy metabolism that involves molecular mechanisms shifting cancer cells to aerobe glycolysis. Our goal was to evaluate the correlation between mutation in the commonly mutated tumor suppressor gene TP53 and metabolism. We established a database comprising mutation and RNA-seq expression data of the TCGA repository and performed receiver oper...

Many food plants accumulate oxalate, which humans absorb but do not metabolize, leading to the formation of urinary stones. The commensal bacterium Oxalobacter formigenes consumes oxalate by converting it to oxalyl-CoA, which is decarboxylated by oxalyl-CoA decarboxylase (OXC). OXC and the class III CoA-transferase formyl-CoA:oxalate CoA-transferase (FCOCT) are widespread among bacteria, includ...

On-off cycles of production wells, especially in bank filtration settings, cause oscillations in the local water table, which can deliver significant amounts of dissolved oxygen (DO) to the shallow groundwater. The potential for DO introduced in this manner to oxidize manganese (Mn), mediated by the obligate aerobe Pseudomonas putida GB-1, was tested in a column of quartz sand fed with anoxic i...

On-off cycles of production wells, especially in bank filtration settings, cause oscillations in the local water table, which can deliver significant amounts of dissolved oxygen (DO) to the shallow groundwater. The potential for DO introduced in this manner to oxidize manganese(II) (Mn(II)), mediated by the obligate aerobe Pseudomonas putida GB-1, was tested in a column of quartz sand fed with ...

Background and Aim: The aim of this in vivo study was to evaluate the microbial flora in infected root canals after the treatment with and without calcium hydroxide (Ca(OH)2) dressing using hand and rotary instruments. Subjects and Methods: Twenty-eight patients were selected. After access cavity preparation completed, the first culture were taken from each root canal with sterile paper points....

Fifteen of 23 ATCC strains and 2 of 9 clinical isolates of Xanthomonas maltophilia, all of which grew aerobically on ammonia, but not nitrate, as a sole nitrogen source, reduced nitrate to nitrite. X. maltophilia failed to grow anaerobically on complex medium with or without nitrate, so it is considered an obligate aerobe. Nitrate-reducing strains contained reduced methyl viologen nitrate reduc...

There are many more phyla of microbes than of macro-organisms, but microbial biodiversity is poorly understood because most microbes are uncultured. Phylogenetic analysis of rDNA sequences cloned after PCR amplification of DNA extracted directly from environmental samples is a powerful way of exploring our degree of ignorance of major groups. As there are only five eukaryotic kingdoms, two clai...

Methylobacterium sp. strain CM4, an aerobic methylotrophic alpha-proteobacterium, is able to grow with chloromethane as a carbon and energy source. Mutants of this strain that still grew with methanol, methylamine, or formate, but were unable to grow with chloromethane, were previously obtained by miniTn5 mutagenesis. The transposon insertion sites in six of these mutants mapped to two distinct...

In response to present and future fossil resource depletion, chemicals production from an alternate raw materials base must be considered. The biologically catalysed degradation of photos:ynthetically stored energy, such as starch and ligno-cellulosics, is an important approach for chemicals production. The objective of this study is to increase the productivity of acrylate from propionate, usi...

Abstract Introduction In the developing phase of complex health intervention: Physical Activity to reduce Vascular Erectile Dysfunction (PAVED), it is crucial explore whether men can accept communicative component regarding information that regular aerobe (i-PAVED). This provided by professionals (HPs) in cardiac rehabilitation, where sexuality issues such as erectile dysfunction (ED) are other...