The question of whether there is a right-hemisphere dominance in the processing of auditory spatial information in human cortex as well as the role of the corpus callosum in spatial hearing functions is still a matter of debate. Here, we approached this issue by investigating two late-callosotomized subjects and one subject with agenesis of the corpus callosum, using a task of sound lateralizat...

The objective of this study was to assess the feasibility of using the frontal suture as an acoustic window to visualize sonographically the midline cerebral structures (transfrontal view) in midtrimester fetuses. The study design was prospective and observational. In 124 healthy fetuses and in 2 fetuses with agenesis of the corpus callosum at 19 to 24 weeks' gestation, an attempt was made to o...

While the processing of verbal and psychophysiological indices of emotional arousal have been investigated extensively in relation to the left and right cerebral hemispheres, it remains poorly understood how both hemispheres normally function together to generate emotional responses to stimuli. Drawing on a unique sample of nine high-functioning subjects with complete agenesis of the corpus cal...

OBJECTIVES: Approximately 20% of BALB/cCF mice are born with partial or total absence of the corpus callosum. Here, we analyzed testosterone and free thyroxin blood levels in adult male mice of this strain in order to see if these hormones are related to the incidence of callosal defects. METHODS: Blood collected from the axillary blood vessels of 12 normal and 10 acallosal deeply anesthetized ...

While some individuals with agenesis of the corpus callosum can perform normally on standardized intelligence tests, clinical observations suggest that they nevertheless have deficits in the domains of fluid and social intelligence. Particularly important for social competence is adequate understanding and use of paralinguistic information. This study examined the impact of callosal absence on ...

Corpus callosum malformation and dysfunction are increasingly recognized causes of cognitive and behavioral disability. Individuals with agenesis of the corpus callosum (AgCC) offer unique insights regarding the cognitive skills that depend specifically upon callosal connectivity. We examined the impact of AgCC on cognitive inhibition, flexibility, and processing speed using the Color-Word Inte...

Two split-brained subjects, one (L.B.) with full forebrain commissurotomy and one (R.B.) with callosal agenesis, and a group of twenty neurologically intact subjects were tested in three discrimination tasks: a go-no go task, a two-choice task, and a three-choice task. The discriminations were based on colour in Experiment 1, and on shape in Experiment 2. The stimuli were presented in one or ot...

AIM The goal of the research was a characteristic of emotional-social competencies and communicative abilities in a 16-years old patient with ACC and Arnold-Chiari disease and higher than average intelligence. METHOD RHLB-PL was applied. RESULTS Total score in RHLB-PL suggested language and communication impairment. The greatest problems were observed in the field of behavioral self-control...

An 18 years old young patient with no history presented to the emergency department suffering from episodes of generalized seizures and atypical headache without fever, the onset of symptoms dated back to two months. The clinical examination was normal. CT scan showed an inter hemispheric fat density ovoid formation, measuring about 40x30cm along major axis, compressing the ventricular junction...