A series of 54 liver biopsy specimens was studied by means of the argyrophil (AgNOR) technique for nucleolar organiser region (NOR)-associated proteins. These included normal livers and livers affected by chronic active hepatitis, cirrhosis, hepatocellular carcinoma and adenoma. Four of the cases of cirrhosis showed liver cell dysplasia. The mean numbers of NOR sites in normal, cirrhotic, and c...

AIM To define the distribution of proliferating cell nuclear antigen (PCNA) and silver staining nucleolar organiser regions (AgNORs) in Hodgkin's disease. METHODS PCNA was shown in a series of 34 cases of Hodgkin's disease using immunohistochemical methods. In a second series of 46 cases the AgNOR technique for interphase nucleolar organiser regions was studied. Both series comprised routinel...

It has been shown that AgNOR staining can provide useful information for diagnosis in cytology of the oral cavity [22], body fluids [3,18], hematologic smears [10,11,14–17] or lymph node aspiration cytology [12]. We would like draw attention of the readers towards an easy AgNOR evaluation which has shown to be very useful as prognostic marker in chronic lymphoid leukemia (CLL) patients. This di...

Aim: In this study, it was aimed to examine the time and dose dependent effects of Ginseng (Panax quinquefolius) on MDA-MB-231 cell lines. Material Methods: breast cancer line used in study. cells were exposed ginseng at 37°C 5% CO2 for varying durations (24 48 hours) doses (1 2 μg/ml ginseng). At end incubation period, viability, apoptosis, cycle Argyrophilic nucleolar organizing region (AgNOR...

U bladder cancer is a common disease. In Iraq, it represents 12.3% of cancer cases among men, and 4.9% of cancer cases among women.1 Cytological examination of urinary specimens is a relatively simple diagnostic procedure that can aid in the diagnosis of disease anywhere in the urinary tract; and nowadays, examination of urine cytology is regarded as part of the routine investigation of patient...

The karyotype and other chromosomal characteristics the crucian carp (Carassius carassius (Linnaeus, 1758)) were revealed by means of conventional banding protocols (C, CMA3, AgNOR). The diploid chromosome number (2n) in this species was 100. Its karyotype was composed of 10 pairs of metacentric, 18 pairs of submetacentric and 22 pairs of subtelo- to acrocentric chromosomes without any microchr...

AIMS The nucleolus is an important cellular component involved in the biogenesis of the ribosome. This study was performed in order to validate the introduction of the argyrophilic nucleolar organiser region (AgNOR) stain technique, specific for the nucleoli detection, in neuropathological studies on sudden fetal and infant death. METHODS In a wide set of fetuses and infants, aged from 27 ges...

Oral Squamous cell carcinoma (OSCC) accounts for over 90% of oral cancer cases and a small percentage of these cases are thought to develop from potentially malignant disorders. Main etiological factor associated with OSCC is smoking. It’s a well known fact that in chronic smokers nuclear alterations are evident. There is a correlation between nucleolar function, size and cell doubling time in ...