The Clonal Selection Algorithm (CSA) is a widely used Artificial Immune Optimization (AIO) approach that tends to mimic the immune response when the pathogenic pattern is detected by the immune cells. However, this method, in its standard form, shows slow convergence and frequently traps in one of the local optima, especially for high dimensional problems. Hence, in this paper, an improved CSA ...

Let A be an n-square (0, 1)-matrix, let ri denote the i-th row sum of A, i = 1 ..... n, and let per(A) denote the permanent of A. Then per(A) ~< H ri q~/-2,.1 I + V T where equality can occur if and only if there exist permutation matrices P and Q such that PAQ is a direct sum of l-square and 2-square matrices all of whose entries are 1. I f A = (ai~) is an n-square mat r ix then the permanent ...

The treatment of rectal cancer has evolved dramatically through the last three decades. Until the 1970’s and 1980’s, surgery was often the only therapeutic modality employed in the treatment of rectal cancer patients. However, local recurrence with surgery alone was significant resulting in patient morbidity and death (Gunderson & Sosin, 1974; Rich et al., 1983). Some studies have demonstrated ...

In order to construct a more universal model for understanding the genetic requirements for bacterial AsIII oxidation, an in silico examination of the available sequences in the GenBank was assessed and revealed 21 conserved 5-71 kb arsenic islands within phylogenetically diverse bacterial genomes. The arsenic islands included the AsIII oxidase structural genes aioBA, ars operons (e.g., arsRCB)...

This paper reviews our applications of longvaccine resulted in high antibody titers and caused infertility acting implantable steroids and immunocontraceptives in in most mares for 2 years. Federal scientists have selected wild ungulates. We implanted captive white-tailed experimented with implantina melenaestrol acetate (MA) in deer ooes w tn ~evonorgestrr O, I a o nor s,ccessl, free-rang ng e...

BACKGROUND The low incidence and the variable presentation complicate clinical investigations on biliary tract cancer. The results of Valle et al. in 2009 provided, for the first time, an evidence-based palliative treatment for this rare tumor type. So far no data are available in Germany regarding the current daily care practice. METHODS We started this national survey in May 2011, including...

Research in Decision-Based Design (DBD) has traditionally modeled the interaction between enterprise product planning and engineering product development in a single optimization problem and solved it using an All-in-One (AIO) approach. Such an approach is not practical in a typical industry design environment, due to the organizational and computational complexities involved. In this paper, we...

Neoadjuvant treatment in terms of preoperative radiotherapy reduces local recurrence in rectal cancer, but this improvement has little if any impact on overall survival. Currently performed optimal quality-controlled total mesorectal excision (TME) surgery for patients in the trial setting can be associated with very low local recurrence rates of less than 10% whether the patients receive radio...

Objective: A patient with oral cancer receives prosthesis, which can help them achieve optimum esthetic, function and form through total oral rehabilitation. Maxillofacial Prosthodontists (MFPs) plays an important role in the management of head and neck cancer patients from the preliminary stage of treatment planning. However, their role is often less understood. The objective of the article is...

PURPOSE The aim of this study is to identify factors associated with the decision to perform an abdominoperineal resection (APR) and to assess if these factors or the surgical procedure itself is associated with circumferential resection margin (CRM) involvement, local recurrence (LR), overall survival (OS) and cancer-specific survival (CSS). PATIENTS AND METHODS The Swedish Rectal Cancer Tri...