The efficacy of a novel, proprietary topical formulation of ibuprofen 5% gel (Ibugel) was evaluated in a placebo-controlled study in patients with soft tissue injuries. Patients received either active gel (n=40) or placebo gel (n=41) for a maximum of seven days. Pain and interference with physical activity were assessed daily using visual analogue scales. There was a significant difference (p<0...

Despite a lot of research, the etiology and progression of breast cancer remain incompletely understood. Recently, human cytomegalovirus (HCMV) was reported as a risk factor for breast cancer. The aim of this study was to know whether breast cancer could be caused by cytomegalovirus or not? In this experiment seventeen samples of RAZI/A mice with spontaneous breast cancer were being gathered fr...

Fast neutrons and protons undergo fundamentally different interactions in tissue. The former interact with nuclei, while the latter, as in the case of photons, interact mainly with atomic electrons. Protons do, however, also undergo some nuclear interactions, the probability of which increases with energy. For both modalities the practical instruments for determining the reference absorbed dose...

The present study aimed to investigate the potential role of leptin in the progression of breast cancer and the associated cell proliferation signalling pathway(s). A total of 44 female patients diagnosed with breast cancer and 24 healthy donors from Ain Shams University Hospitals (Cairo, Egypt) were enrolled in the present study. The present study assessed leptin expression in breast cancer ti...

BACKGROUND Numerous studies have demonstrated that the levels of prostaglandins are greater in various cancers, including breast cancer and colon cancer, than in normal tissues. In particular, the inducible form of cyclooxygenase (COX), the rate-limiting enzyme in prostaglandin biosynthesis, is overexpressed in colon tumors. Epidemiologic studies have demonstrated that the use of aspirin or oth...

Transillumination in the diagnosis of breast disease was first used about 50 years ago.'-3 The sinus diaphanograph is a recent development that provides a light beam of variable intensity. When it is used at the lowest possible setting small lesions become capable of light interference and more subtle changes in tissue density can be visualised. Diaphanoscopy is performed in a totally darkened ...

Transillumination in the diagnosis of breast disease was first used about 50 years ago.'-3 The sinus diaphanograph is a recent development that provides a light beam of variable intensity. When it is used at the lowest possible setting small lesions become capable of light interference and more subtle changes in tissue density can be visualised. Diaphanoscopy is performed in a totally darkened ...

PURPOSE Intracavitary brachytherapy (ICB) is a widely used technique in the treatment of cervical cancer. In our Institute, we use different reconstructive methods in the conventional planning procedure. The main aim of this study was to compare these methods using critical organ doses obtained in various treatment plans. There is a small difference in the recommendations in selecting bladder d...

Introduction: Hypothyroidism is one of the frequent side effects of radiotherapy of head and neck cancers, breast cancer, and Hodgkin's lymphoma. It is recommended to estimate the normal tissue complication probability of thyroid gland using radiobiological modeling during treatment planning. Moreover, the use of artificial neural network is also proposed as a new method for t...

adiponectin is one of the most important members of adipokine family which is widely synthesized and secreted by adipose tissue. the action of adiponectin is via binding to main receptors. it has several actions including regulation of glucose level, lipid homeo­stasis and reproductive system. adiponectin can also influence vascular endothelium via preventing the migration of monocytes. the rol...