In vitro treatment of Echinococcus multilocularis and Echinococcus granulosus larval stages with the antimalarials dihydroartemisinin and artesunate (10 to 40 microM) exhibited promising results, while 6 weeks of in vivo treatment of mice infected with E. multilocularis metacestodes (200 mg/kg of body weight/day) had no effect. However, combination treatments of both drugs with albendazole led ...

We present rupture of lung hydatid cyst in a patient with multiple organ involvement during albendazole treatment. The patient was first provided mechanical ventilation than residue cavity and the other intact cyst was treated surgically. We concluded that albendazole should be used in postoperative period in patients with hydatid disease of the lung to prevent recurrent disease. q 2002 Elsevie...

Various anthelmintics belonging to the pharmacolog~cal group of benzimidazoles (oxibendazole, thiabendazole, albendazole, oxfendazole, flubendazole, mebendazole, parbendazole, fenbendazole and triclabendazole) were tested and compared for their In vitro and in vivo activity against an infection of rainbow trout Onchorhynchus myhss by Gyrodactylus. The trout were also observed for signs of toxic...

Background Hydatid cyst is an endemic disease frequently localized to the liver. It is frequently observed in Southeast Europe, Middle East, and Turkey. Although the cyst rupture can occur spontaneously, it can also occur upon albendazole treatment. Its surgical treatment includes cystotomy, capitonnage, and wedge resection. Material-Method A 56-year-old male immigrant was admitted with fever...

The presumptive treatment of parasitosis among immigrants with albendazole has been shown to save both money and lives, primarily via a reduction in the burden of Strongyloides stercoralis. Ivermectin is more effective than albendazole, but is also more expensive. This coupled with confusion surrounding the cost-effectiveness of guiding therapy based on eosinophil counts has led to disparate pr...

Anthelmintic treatment, which is recommended during pregnancy in areas where there is a high rate of anaemia, needs further investigation. We examined prospectively the association between anthelmintic treatment and maternal anaemia, birthweight, and infant mortality in a study of prenatal supplements, in which women received albendazole twice during pregnancy. Women given albendazole in the se...

Neurocysticercosis (NC) is a common parasito­ sis affecting the central nervous system. It is en­ demic in many developing countries. PraziquanteI was the first drug to show potential efficacy for treatment of NC (Sotelo et ai, 1984). Recently albendazole, an imidazole with activity against in­ testinal and systemic infections by trematodes and cestodes (Anonymous, 1984), demonstrated its effic...

Hypereosinophilia is usually defined as a blood eosinophil count >1500/μL. A broad variety of conditions are associated with hypereosinophilia. The present report describes three cases of hypereosinophilia, in which a thorough history, physical examination, laboratory and imaging investigations were unable to detect any abnormalities. Albendazole was empirically administered in all three cases,...