Introduction According to DSM V, substance-induced psychotic disorder is a mental health condition in which the onset of symptoms can be traced use psychotropic substance. The pathogenesis this disease still poorly understood; current literature traces its causes back genetic predisposition and early traumatic events (i.e. child abuse). Objectives present study aims identify specific clinical f...

AIMS (i) To evaluate the prevalence of alcohol use disorders, and at risk-drinking among outpatients admitted to the Division of Psychiatry, University of Cagliari, Italy, for mood disorders, and (ii) to compare the sensitivity and specificity of the questionnaires used. METHODS Fifty-six patients affected by mood disorders answered to the questions of (i) The NIAAA Guide for identification o...

The role of alcohol-related risk perception for effective treatment of alcohol use disorders (AUD) is still unclear. The present study on 101 alcohol-dependent patients undergoing a 10-week AUD treatment protocol investigated the relationship between alcohol-related risk perception and alcohol use with the hypotheses that (1) risk perception changes across treatment, (2) changes vary with treat...

Alcohol use disorder (AUD) is a common mental that may cause dementia and mood disorders such as anxiety. The dentate gyrus (DG) key brain region for well anxiety, while the underlying mechanisms of DG-based behavioral impairments induced by ethanol are not fully understood. Here we report behavior inhibition using vapor exposure procedure combined with tasks. results indicate single leads to w...

Prenatal alcohol exposure is strongly associated with disruptive behaviour in childhood and antisocial behaviour later in life. There are numerous confounding risk factors in the lives of alcohol-abusing mothers that may contribute to the behaviour problems seen in their children, rather than direct brain injury by alcohol. In fact, many of these additional environmental and genetic risk factor...

Alcohol use disorders (AUDs) are a health problem of high prevalence in most communities and such problems account for 5% of the total burden of disease worldwide. Clinical toxicologists are commonly required to treat patients having AUDs and associated drug/alcohol-related harm. There have been recent changes to some of the diagnostic criteria (notably in DSM V) relevant to AUDs, with older te...

Background: Alcohol abuse is involved in the pathogenesis of multiple organ disorders; the underlying mechanism is incompletely understood. The ubiquitin editing enzyme A20 is involved in regulating activities in the cell. Suppression of A20 is suggested as one factor in the initiation of inflammation. This study investigates the mechanism by which chronic alcohol consumption modulates the leve...

UNLABELLED Adolescent suicide is a major social and medical problem. Alcohol use disorders with comorbid major depression represent an especially high-risk profile for suicidal behavior, repeated suicidal behavior and completed suicide. We compared demographic and clinical characteristics, prevalence of interpersonal triggers and the number of triggers for suicidal behavior in depressed late ad...