نتایج جستجو برای: alcohol intake

تعداد نتایج: 215740  

Journal: :Journal of epidemiology and community health 1983
J T Salonen J Tuomilehto A Tanskanen

The association of blood pressure with reported intake of salt, saturated fats, and alcohol was studied in a sample of 8479 subjects based on a cross sectional survey in a population aged 30 to 64 years. A consistent association was found between the mean arterial pressure and the intake of alcohol (p less than 0.001) and saturated fats (p less than 0.01). There was also a weak association betw...

2015
Yi Wei Lim Nathan P. Meyer Alok S. Shah Matthew D. Budde Brian D. Stemper Christopher M. Olsen

Alcoholism is a frequent comorbidity following mild traumatic brain injury (mTBI), even in patients without a previous history of alcohol dependence. Despite this correlational relationship, the extent to which the neurological effects of mTBI contribute to the development of alcoholism is unknown. In this study, we used a rodent blast exposure model to investigate the relationship between mTBI...

Journal: :Kathmandu University medical journal 2008
S N Pradhan S R Adhikary S C Sharma

OBJECTIVE The aim of the work was to study the socio-demographic variables and their co-morbidity to alcohol consumption and presence of depressive symptomatology. DESIGN This was a prospective cross-sectional study. MATERIALS AND METHODS The study was carried out in 53 patients, who were admitted in the wards of Kathmandu Medical College Teaching Hospital (KMCTH) with the diagnosis of ment...

Journal: :Addiction biology 2016
Maria Garbusow Daniel J Schad Miriam Sebold Eva Friedel Nadine Bernhardt Stefan P Koch Bruno Steinacher Norbert Kathmann Dirk E M Geurts Christian Sommer Dirk K Müller Stephan Nebe Sören Paul Hans-Ulrich Wittchen Ulrich S Zimmermann Henrik Walter Michael N Smolka Philipp Sterzer Michael A Rapp Quentin J M Huys Florian Schlagenhauf Andreas Heinz

In detoxified alcohol-dependent patients, alcohol-related stimuli can promote relapse. However, to date, the mechanisms by which contextual stimuli promote relapse have not been elucidated in detail. One hypothesis is that such contextual stimuli directly stimulate the motivation to drink via associated brain regions like the ventral striatum and thus promote alcohol seeking, intake and relapse...

2012
Wei Ge Jun Ren

Mitochondrial aldehyde dehydrogenase-2 (ALDH2) has been shown to benefit myopathic changes following alcohol intake, although the precise mechanism is still unclear. This study was designed to evaluate the role of ALDH2 on chronic alcohol intake-induced myocardial geometric and functional damage with a focus on autophagic signalling. Wild-type friendly virus B (FVB) and transgenic mice overexpr...

2018
Linda K. McEvoy Christine Fennema-Notestine Jeremy A. Elman Lisa T. Eyler Carol E. Franz Donald J. Hagler Sean N. Hatton Michael J. Lyons Matthew S. Panizzon Anders M. Dale William S. Kremen

Heavy alcohol consumption is associated with deleterious changes in the brain but associations of moderate alcohol intake are not well understood. We examined the association of alcohol consumption with brain white matter health in 377 middle-aged men (56-66 years old; mean 61.8 ± 2.6 years) who were participants in the Vietnam Era Twin Study of Aging (VETSA). T1-, T2-, proton density-, and dif...

2012
Heidi M. B. Lesscher Julia M. Houthuijzen Marian J. Groot Koerkamp Frank C. P. Holstege Louk J. M. J. Vanderschuren

Alcoholism is a devastating brain disorder that affects millions of people worldwide. The development of alcoholism is caused by alcohol-induced maladaptive changes in neural circuits involved in emotions, motivation, and decision-making. Because of its involvement in these processes, the amygdala is thought to be a key neural structure involved in alcohol addiction. However, the molecular mech...

Journal: :Journal of forensic and legal medicine 2013
Kai-Uwe Schmitt Christian Lanz Markus H Muser Felix Walz Urs Schwarz

OBJECTIVES The influence of low-dose alcohol intake on reflexive visually guided saccades was investigated. METHODS 40 healthy human subjects were orally given alcohol resulting in low-dose alcohol concentration (less than 0.8‰) blood alcohol concentration. Before and after exposure, horizontal saccadic eye movements were recorded at several points in time. The recordings were evaluated with ...

Journal: :Journal of cardiovascular pharmacology 1990
S Mizushima Y Nara M Mano M Sawamura R Horie Y Yamori

The relationship between alcohol consumption and blood pressure (BP) was studied in 29 centers in 12 countries as part of the International Cooperative Cardiovascular Diseases and Alimentary Comparison (CARDIAC) Study. From each population, 100 men and 100 women aged 50-54 were randomly selected for BP measurement by automated system and for a standardized interview to complete the questionnair...

Journal: :Alcohol and alcoholism 2005
Gian Luigi Gessa Salvatore Serra Giovanni Vacca Mauro A M Carai Giancarlo Colombo

AIMS The present study investigated the effect of the newly synthesized cannabinoid CB(1) receptor antagonist, SR147778, on alcohol intake and the motivational properties of alcohol in selectively bred Sardinian alcohol-preferring (sP) rats. METHODS AND RESULTS In Experiment 1, the repeated administration of SR147778 (0.3-3 mg/kg twice daily, i.p.) specifically suppressed the acquisition of a...

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