BACKGROUND Cisplatin is one of the most effective chemotherapeutics against a wide range of cancers including head, neck, ovarian and lung cancers. But its usefulness is limited by its toxicity to normal tissues, including cells of the kidney proximal tubule. The purpose of the present study is to investigate whether the hydro-alcoholic extract of Rubia cordifolia could decrease the intensity o...

The eucalyptus tree is an excellent source of antimicrobial agents; it used in many oral cure products. bitter taste these agents could compromise their usage. Therefore, fortifying the extracts with non-nutritive sweeteners be a promising procedure for masking unpleasant taste. This study was vitro evaluation activity (alcoholic and aqueous) against salivary Streptococci mutans. It aimed to in...

Aqueous and alcoholic extracts of curcuma amda roxb. rhizomes have been evaluated for its anti tumour activity in Swiss albino mice. Alcoholic extract exhibited more potent anti tumour activity than aqueous extract. In-vitro cytotoxicity studies were confirmed by brine shrimp bioassay method. A significant increase in the life span and a decrease in the cancer cell number and tumour weight were...

background: phytoestrogens are some plant compounds with estrogenic biological effects which are found in many nutritional sources as soybean, flaxseed and sesame. vitex agnus-castus, also called vitex, owns phytoestrogenic properties. studies have showed that phytoestrogens have different impacts on the gestation process and reproduction indices. the present study is aimed at investigating the...

Alcoholic and chloroform extracts of E. albaT. purpurea and B. diffusa were screened for antihepatotoxic activity. The extracts were given after the liver was damaged with CCl4. Liver function was assessed based on liver to boy weight ratio, pentobarbitone sleep time, serum levels of transaminase (SGPT, SGOT), alkaline phosphatase (SALP) and bilirubin. Alcoholic extract of E. alba was found to ...

The flower buds of Syzygium aromaticum (clove) have been used as traditional medicine for the treatment of male sexual disorders in Asian countries. Recently, there are some reports about the effects of the clove on reproductive activities in mammals. Therefore, its effect on testicular function was examined in male golden hamsters whose reproductive activity is inhibited by photoperiod such as...

The importance of Tinospora cordifolia stem extract was investigated for its possible curative effect in male wistar rats against the cisplatin induced nephrotoxicity. Oral administration of plant extract cured the cisplatin induced kidney damage. There was an increase in serum creatinine, blood urea nitrogen and alkaline phosphatase in rats treated with Cisplatin (5mg/kg body weight, i.p). Adm...

regarding the therapeutic properties of nigella sativa (ns), the effects of the plant hydro – alcoholic extract on learning, memory and brain tissues oxidative damage were investigated in penthylenetetrazole (ptz) - induced repeated seizures.there were 4 experimental groups including: 1- control group; received saline, 2- ptz group ; received saline and ptz (50 mg/kg, i.p) , 3-ptz- ns 200 and 4...

The anticancer potential of Cuscuta reflexa (whole plant extract), a holoparasitic plant collected from its host plant Euphorbia royleana was evaluated by testing its in vitro cytotoxicity and induction of cell death by apoptosis. Among three extracts (95% alcoholic, 50% hydro-alcoholic and aqueous extracts) and four fractions (n-hexane, chloroform, n-butanol and water) of alcoholic extract, th...

Foeniculum vulgare Mill. commonly known as fennel, belongs to family Apiaceae. The aqueous and alcoholic seed extracts of Foeniculum vulgare Mill. were evaluated for their antifungal activity against Alternaria alternata, Mucor rouxii and Aspergillus flavus. The method used for determination of antifungal activity of both aqueous and alcoholic seed extracts was agar well diffusion method. The a...