In Part 1, we discussed the etiology and epidemiology of allergy. 1 This second part will focus on the diagnosis and treatment of allergies. Diagnosing an allergy is much fike detective work. The physician gleans clues from the case history, and confirms the clinical impression by using allergy tests that help determine the cause of the patient’s problems. Recent progress in understanding the b...

Cow’s milk allergy (CMA) is one of the most common food allergies in first years life. CMA classified as immunoglobulin E (IgE)or non-IgE-mediated reactions. IgE-mediated reactions are typically immediate onset, with symptoms manifesting within 2 hours after ingestion. However, delayed and mostly occur between 48 post exposure. This report describes a 17-year-old who presented long-standing his...

CoMiSSTM is a clinical tool developed to increase awareness among healthcare professionals (HCP) of possible symptoms cow’s milk allergy (CMA) in infants. During this symposium, leading experts the field paediatric gastroenterology, allergy, and nutrition highlighted how CoMiSS can facilitate CMA support HCPs improving patient journey from symptom presentation diagnosis. Rosan Meyer, Imperial C...

Over 80% of weekday time is spent indoors and the air quality of this environment may affect the incidence of symptoms in allergy sufferers. However, indoor/outdoor measurements have been jointly considered only in a few studies. The objective of this paper is to analyse indoor/outdoor biological and non-biological particle content togeher with other factors affecting the severity of symptoms d...

BACKGROUND There have been several reports on neonates with milk allergy in a neonatal ward. This type of allergy is mostly categorized as a non-IgE-mediated food allergy. Although most cases of milk allergy occur in the first few months of life, the differences in clinical characteristics between premature and full-term neonates are still unclear. OBJECTIVE This study aimed to clarify the di...

Food allergy can appear at any age but true allergies to food are more common in infants and young children. Food allergies are the earliest manifestation of atopy (the tendency to develop allergy) in infants and children. A limited number of foods are responsible for the vast majority of food induced allergic reactions. In children the main foods are cow milk, egg, peanut, fish, tree nuts, whe...

Oral allergy syndrome (OAS) is defined as the symptoms of IgE-mediated immediate allergy localized in the oral mucosa, and the characteristics depend on the lability of the antigen. Another term used for this syndrome is pollen-food allergy (PFS); the patient is sensitized with pollen via the airways and exhibits an allergic reaction to food antigen with a structural similarity to the pollen (c...

In recent years, we have been observing an increased proportion of atopic diseases in children after solid organ transplantation. The pathogenesis of post-transplantation allergy is not completely understood and probably involves several factors, including immunosuppressive therapy. In this paper we present a case of 3-year old boy, after orthotopic heart transplantation at 6 months of age, wit...

Exposure to indoor allergens is an important risk factor for sensitisation and respiratory allergy. The aim of this paper was to evaluate the levels of mite, cat and latex allergens in dust collected from an indoor workplace and to assess whether the exposure to these allergens was associated with the allergy symptoms reported by employees. Sixty dust samples were collected. Allergen concentrat...

Allergy to human seminal plasma (HSP) is rare. It presents with a variety of symptoms, ranging from localized changes to generalized reactions or even anaphylactic shock. Symptoms typically start within minutes to one hour after exposure. Diagnosis is based on history, evidence of specific IgE antibodies and skin prick testing (SPT). A 25-year-old Caucasian woman presented with eyelid swelling,...