Hairy cell leukemia (HCL), comprising 2% of all leukemias, is a chronic disorder characterized by mononuclear cells with prominent cytoplasmic projections. For years, patients with HCL underwent splenectomies and then interferon alpha for treatment, which provided high response rates but low percentages of complete remission. More recent treatments with 2-chlorodeoxyadenosine result in 85%-90% ...

We consider extending the AIXI agent by using multiple (or even a compact class of) priors. This has the benefit of weakening the conditions on the true environment that we need to prove asymptotic optimality. Furthermore, it decreases the arbitrariness of picking the prior or reference machine. We connect this to removing symmetry between accepting and rejecting bets in the rationality axiomat...

In this position paper we describe an interface to incorporate application-specific knowledge for conflict resolution in an optimistically replicated file system. Conflicts arise in such systems because replicas of an object can be modified simultaneously in different network partitions. Application-specific knowledge is made available by the application writer in specialized tools called Appli...

Optimism is a well-known technique to enhance the performance of distributed protocols. Optimistic approaches exploit properties exhibited by the system with certain likelihood, (i.e., that certain kinds of scenarios will prevail over others) to outperform the corresponding conservative protocol. These properties are usually referred as optimistic assumptions (e.g., an optimistic assumption is ...

The use of versioned data has proven its value in many areas of Computer Science including concurrency control. In this paper we examine the use of versioned objects in object bases for the purpose of enhancing concurrency. We provide a framework for discussing multi-version objects which includes fundamental de nitions, the abstraction of objects as automata and a model of object method execut...