Background Diabetes-associated cognitive dysfunction (DACD) is a common and serious complication in diabetes has high impact on the lives of both individuals society. Although number research focused DACD past two decades, there no study to systematically display knowledge structure development field. Thus, present aimed show landscape identify emerging trends for assisting researchers or clini...

Background: Behavioral variant frontotemporal dementia (bvFTD) patients show prefrontal cortex dysfunction and atrophy. Methods: We investigated whether executive function in conjunction with prefrontal cortex atrophy discriminates bvFTD and Alzheimer’s disease (AD) patients efficiently at presentation. Results: AD and bvFTD patients were distinguishable by 89.5% on their performance of 3 execu...

The most popular animal models of Alzheimer’s disease (AD) are transgenic mice expressing human genes with known mutations which do not represent the most abundant sporadic form of the disease. An increasing number of genetic, vascular and psychosocial data strongly support that the Octodon degus, a moderate-sized and diurnal precocial rodent, provides a naturalistic model for the study of the ...

Background: Alzheimer’s disease (AD) is a neurodegenerative disorder greatly influenced by oxidative stress and mitochondrial dysfunction which may lead to deposition of β-amyloid (Aβ) peptides. Protein malnutrition increases oxidative damage in cortex, hippocampus and cerebellum. Epigallocatechin-3-gallate (EGCG) has health-promoting effects in CNS, while Coenzyme Q10 (CoQ10) is intracellular ...

Background Longitudinal changes in volumetric MRI (vMRI) are correlated with longitudinal cognition and function subjects Alzheimer’s disease (AD). In clinical trials, vMRI has been used as an exploratory outcome measure the assumption that effective treatment would slow down brain atrophy, addition to slowing cognitive decline. We have recently shown AD trials published up November 2020, effec...

Alzheimer’s disease (AD) a well-known neurodegenerative disorder characterized by formation of amyloid plaques and neurofibrillary tangles and by loss of neurons is the most common type of Dementia, also called as Senile Dementia of Alzheimer Type (SDAT) which frequently occurs in elder people. Globally it was noticed that every year 3, 60, 000 new cases were admitted with severe AD. AD was fir...