A facile one step synthesis of anilino alky1-N-substituted phthalimide I is reported. The following compounds belonging to this series were made: 1. (anilino-N-ethyl) phthalimide 8 2. (3,4, 5-trimethoxy anilino-N-ethyl) phthalimide 6 3. (3,4, 5-trimethoxy anilino-N-propyl) phthalimide 7 4. N-(ethyl phthalirnido-p-amino benzoyl) glutamic acid diethyl ester 10 5. N-(propyl phthalimido-p-ami...

synthesis of 2-[2-(2,6-dichlorophenyl)amino]phenylmethyl-3-[4-(2-substitutedphenyl-4-oxo-thiazolidinyl)aryl]-6-bromo quinazolin-4(3h)ones via-j have been achieved from the starting material 2-[(2,6-dichlorophenyl)amino] phenylacetic acid i to benzoxazine iii, further reaction with p-phenylindiamine and substituted aromatic aldehyde gave 2-[2-(2,6-dichlorophenyl)amino]phenyl methyl-3-(4-aminoary...

quorum sensing controls the luminescence of vibrio fischeri through the transcriptional activator luxr and the specific autoinducer signal produced by luxi. amino acid sequences of these two genes were analyzed using bioinformatics tools. luxi consists of 193 amino acids and appears to contain five α-helices and six ß-sheets when analyzed by sspro8. luxi belongs to the autoinducer synthetase fa...

Chronic myelogenous leukemia (CML) stem cells are the cellular source of vast majority mature CML and responsible for relapse disease post-tyrosine kinase inhibitor (TKI) therapy. Although cells, whose active division is driven by BCR-ABL1 oncogene-dependent signaling, reduced TKI therapy, resistant because they become quiescent via a heretofore elusive mechanism that independent oncogene signa...

persian sturgeon (acipenser persicus) is a valuable fish caught in the caspian sea. in this study, effect of frying, the most common cooking methods on nutritional properties of the persian sturgeon fillet were investigated. the raw and fried samples were analyzed for amino acid composition, protein and fat content, in vitro digestibility and nutritional parameters. the results showed that the ...

The sp3 C–H acetoxylation at the β-position of α,α-disubstituted α-amino acids proceeds smoothly under palladium catalysis in presence PhI(OAc)2. This reaction provides a straightforward synthetic route to non-natural β-acetoxy-α-amino acids. α-aminocyclopropanecarboxylic acid takes place via ring-opening selectively afford an acyclic γ-acetoxy-α,β-unsaturated amino acid.

abstract background: naturally occurred hepatitis b virus (hbv) with surface mutations in a variety of chronic hepatitis b (chb) patients who have received no vaccine or hbig bearing substitutions in surface protein, have been reported. objectives: current knowledge concerning the prevalence of these naturally occurring surface antigen mutations among iranian carriers is limited. patients and m...