Allografts, cadaver skin and amnion membrane are considered the golden standard in the management of partial thickness burns. However, debate on whether the tissue needs to be viable is on-going, since many believe that viable grafts result in better healing. The objective of this literature survey was to analyse the evidence on the method of preservation of allografts (cadaver skin or amnion m...

Emerging evidence suggests human amnion tissue as a valuable source of two distinct types of pluripotent cells, amnion epithelial cells (hAECs) and mesenchymal stromal cells (hAMSCs), for applications in cell replacement therapy. For some approaches, it may be necessary to culture and differentiate these cells before they can be transplanted. No systematic attempt has been yet made to determine...

In vitro studies have shown that amnion-produced growth factors participated in angiogenesis, re-epithelialization, and immunomodulation. The aim of our study was to investigate the growth factors and receptors produced by human amnion tissue and amniotic cells. Human amnions (hAM) were isolated, and amnion circles were dissected for in vitro analysis. Some amnion fragments were digested by the...

Prostate cancer is the most common amongst men, and one of its treatments in localized stage radical prostatectomy (RP). This technique achieves a high success rate regarding oncological results, but main drawbacks are sexual disorders, especially erectile dysfunction, ranging from 14-90% cases. Therefore, surgery advancements last decade have been focused on minimizing impact patient’s functio...

Gingival recession is one of the most common soft tissue problems, especially when it hinders the esthetics of a patient. Gingival recession can further lead to root caries, sensitivity, and difficulty in plaque control. Moreover, exposed roots are prone to abrasion and erosion. Periodontal plastic surgery is one of the emerging fields, which helps to meet such soft tissue problems. Currently, ...

OBJECTIVE In order to elucidate the implication of apoptosis in lactate dehydrogenase (LDH) leakage from influenza virus-infected cells, the effects of a general caspase inhibitor, N-t-Boc-Asp(OMe)-fluoromethylketone (Boc-D-fmk), on LDH leakage, apoptosis induction and virus proliferation were examined. METHODS Cultured human fetal membrane chorion and amnion cells were incubated with or with...