Entamoeba histolytica was first cultured in vitro in 1925 (Boeck and Drbohlav, 1925) but has not yet been grown in the absence of living bacteria. Experimentally the dependence of E. histolytica on living bacteria in the intestine is well illustrated by the inability of E. histolytica to survive and invade the bowel wall of germ-free guinea-pigs (Phillips, Wolfe, Rees, Gordon, Wright, and Reyni...

While colonic and hepatic amoebiasis occur commonly in tropical countries, primary pulmonary amoebiasis remains a rare condition. Pulmonary involvement, when it occurs, is usually secondary to amoebic liver abscess. Primary pulmonary amoebiasis is thought to occur via haematogenous spread. We report a case of primary pulmonary amoebiasis confirmed by visualizing the trophozoites of entamoeba hi...

Tinidazole as a single drug therapy given in a single dose daily for 5 or 3 days was put to rigorous test in malnourished children. Of 25 children with amoebic liver abscess, 23 were cured. The 2 remaining cases required surgical drainage followed by other amoebicides, one subsequently dying from complicating bronchopneumonia.

Case report A female patient was admitted to our ward for fever 3 days after stopping therapy with ertapenem and metronidazole from a previous hospitalization. From the medical history we mention that the patient had had two other episodes of liver microabscesses which responded well and promptly to antibiotic regimens that had in common metronidazole. The patient was screened for HIV, HTLV, tu...

A 35 years old male presented with a two months history of progressively increasing dyspnoea. On examination he was in respiratory distress, afebrile, had prominent neck veins and an increased area of cardiac dullness. The heart sounds were muffled, and the abdomen was unremarkable except for an enlarged, tender liver. The blood count was normal, but the ESR was raised (60mm). X-ray chest showe...

A variety of hepatic manifestations may occur during attacks of acute amoebic dysentery, conforming to clearly defined clinical groups. The incidence of definite hepatic involvement presenting as cases of hepatic amoebiasis with or without demonstrable pus or with tender hepatomegaly was 57-5%. While it is possible that the cases presenting with hepatic manifestations without demonstrable pus a...

In a recent authoritative work on tropical medicine (1) in the section on amoebic abscess of the liver, emetine is said to have " robbed the surgeon of much of the surgery associated with amoebic inflammations of the liver, which, in any degree short of an actual abscess, will almost certainly yield to this treatment. If an abscess appears to be forming, or has already formed, operation is nece...

introduction: determination of the efficacy of crude entamoeba histolytica extract and its fractions (fi,fii & fiii) in antiamoebic antibody detection by elisa. material and methods: entamoeba histolytica nih:200 was cultured axenically and different fractionsof its crude amoebic extract, i.e. fi, fii & fiii, were obtained by column chromatography. efficacy of crudeand fractioned antigens for a...