The MICs of 24 antimicrobial agents were determined for 335 strains of Yersinia enterocolitica isolated from faeces in the Netherlands during 1982-1991. The isolates belonged to biotypes 1A, 1B, 2, 3, 4 and to serotypes O3, O5.27, O6.3, O7.8, O8, O9. Almost all strains were susceptible to piperacillin, piperacillin/tazobactam, imipenem, all cephalosporins except cefazolin, the aminoglycosides, ...

Melioidosis, which is mainly prevalent in Thailand and Australia, has shown an increasing trend in India in the last few years. We carried out a retrospective study of 25 culture-proven adult cases of melioidosis who were admitted to a tertiary care hospital in southern India during June 2001 to September 2007. There was a six-fold increase in the number of cases in 2006 and 2007 as compared to...

The in-vitro activity of trovafloxacin and nine other antimicrobials was determined for 413 non copy anaerobic clinical isolates. Trovafloxacin was the most active quinolone tested with an MIC90 of 0.5 mg/L against Gram-positive cocci (n = 75); MIC90 of 4 mg/L against Gram-positive bacilli (n = 151); MIC90 of 0.5 mg/L for Gram-negative cocci (n = 12) and MIC90 of 1 mg/L for Gram-negative bacill...

The article presents the rationale for a new therapeutic strategy treatment of patients with COVID-19, based on combined use biologic response modifiers and drugs targeting etiology pathophysiology novel coronavirus infection, excluding disadvantages polypharmacy, providing high clinical effect. This approach has been predominantly used in home health outpatient 324 COVID-19 variable severity u...

Abstract Background Annual point prevalence surveys (PPS) are cornerstones in antimicrobial stewardship (AMS). The National Antimicrobial Prescribing Survey (NAPS) is a web-based qualitative auditing platform that provides standardized and validated tool to assist hospitals assessing the appropriateness of prescribing. Objectives To evaluate usefulness NAPS UK tertiary hospital setting. Methods...