known naturally occurring degradation product may be of interest with respect to the etiology of neural tube defects or the homocysteinemia that is associated with this variant. At a more practical level, the comparative evaluation of the two assays reported here indicates that folate concentrations are not being measured accurately by one of the assays in the 5% to 15% of people who are homozy...

Amperometry has been used for real-time electrochemical detection of the quantal release of catecholamines and indolamines from secretory granules in chromaffin and mast cells. Using improved-sensitivity carbon fiber electrodes, we now report the detection of quantal catecholamine release at the surface of somas of neonatal superior cervical ganglion neurons that are studded with axon varicosit...

Antioxidants are compounds that prevent or delay the oxidation process, acting at a much smaller concentration, in comparison to of preserved substrate. Primary antioxidants act as scavenging chain breaking antioxidants, delaying initiation interrupting propagation step. Secondary quench singlet oxygen, decompose peroxides non-radical species, chelate prooxidative metal ions, inhibit oxidative ...

Abstract In this study, to enhance the selectivity and sensitivity of salbutamol detection performed by a carbon plate electrode, electrode was modified using novel molecularly imprinted polymer (MIP) combined with reduced graphene oxide (RGO). The RGO/MIP combination prepared polymerization methacrylic acid as monomer template. surface morphologies electrodes were studied field-emission scanni...

Abstract The electrochemical regeneration of the reduced form nicotinamide adenine dinucleotide cofactor (NADH) was realized in a hybrid flow reactor coupling fuel cell technology and redox device, paying attention to robust immobilization all catalysts. rhodium catalyst Rh(Cp✶)(bpy)Cl + covalently immobilized on multi‐walled carbon nanotube (MWCNT) layer association with gas diffusion electrod...

We have studied exocytosis in rat peritoneal mast cells by cell-attached patch amperometry. Step increases in capacitance were accompanied by typical amperometric spikes due to the release of 5-hydroxytryptamine (serotonin), indicating exocytosis of typical mast cell granules. We have measured the time course of fusion pore expansion, and correlated it with release from the granule matrix. The ...

Amperometry at a carbon fiber microelectrode modified with a composite of ruthenium oxide and cyanoruthenate was used to monitor chemical secretions of single pancreatic beta cells from rats and humans. When the insulin secretagogues glucose, tolbutamide, and K+ were applied to the cell, a series of randomly occurring current spikes was observed. The current spikes were shown to be due to the d...