BACKGROUND AND OBJECTIVES Several classes of inotropic drugs with different hemodynamic effects are used in the treatment of low cardiac output in patients with diastolic dysfunction undergoing cardiac surgery. The objective of the present study was to compare the effects of dobutamine and milrinone on hemodynamic parameters and oxygen supply in this population of patients. METHODS After appr...

It is a particular pleasure for me to take part in the joint exercises of the Nathan Smith Club and the Beaumont Medical Club on this occasion of the centennial celebration of the demonstration of ether as an anesthetic agent. Being a native of Georgia, but also a house pupil of the Massachusetts General Hospital, I have had somewhat mixed loyalties, and it is good to survey and properly apport...

BACKGROUND An unresolved question is the time required for the ability to return to complex tasks following anesthesia. OBJECTIVES This study aims to characterize the severity and duration of cognitive impairment following sevoflurane or desfluane anesthesia after brief surgery using tests of cognitive ability to objectively testing performance. PATIENTS AND METHODS This study is a double b...

BACKGROUND AND OBJECTIVES Reducing the mass of local anesthetic minimizes the effects of hypotension after spinal anesthesia for cesarean section and the incidence of maternal adverse events preserving fetal well-being, but it may result in insufficient anesthesia. Hypotension associated with greater masses of subarachnoid anesthesia can be controlled by prophylactic continuous infusion of phen...

Intersex fish, antibiotic-resistant bacteria, falling sperm counts, and contamination of drinking water: these are just some of the potential consequences related to the growing problem of pharmaceutical pollution. With the rising use and complexity of modern pharmacologic care, many investigators have focused their efforts on demonstrating that drugs administered to patients will inevitably fi...

INTRODUCTION Employment in the health care industry can be hazardous to one’s health. According to the U.S. Bureau of Labor, health care is second only to manufacturing in the number of occupational illnesses and injuries sustained by their workers. Anesthesia personnel are at risk of acquiring a number of occupational illnesses and injuries that are endemic to the high intensity environment of...

The umbilical artery and jugular venous blood gases of the first five neonatal puppies born from nine healthy bitches by elective caesarean section, were analyzed to determine whether the order of birth had any influence over the evaluated parameters. Anesthesia was induced with propofol (6.0 mg kg-1, IV) followed by epidural injection of 2% lidocaine chloride (5.0 mg kg-1). Additional boluses ...