نتایج جستجو برای: animal testing alternatives
تعداد نتایج: 580515 فیلتر نتایج به سال:
Aerobic fitness is an important determinant of overall health. Higher aerobic fitness has been associated with many health benefits. Because myocardial ischemia is rare in children, indications for exercise testing differ in children compared with adults. Pediatric exercise testing is imperative to unravel the physiological mechanisms of reduced aerobic fitness and to evaluate intervention effe...
Problem of nuclear power plant (NPP) safe operation and risks reducing for nuclear power plants is one of the most actual ones. Taking into account the fact that NPP unit lifetimes are being extended beyond their design period, this problem becomes more and more important. One of the main and critical subsystems for NPP safe operation is steam generator (SG) consisting of (except other systems)...
Alternative Methods to Animal Testing for the Safety Evaluation of Cosmetic Ingredients: An Overview
The safety of cosmetics sold in Europe is based on the safety evaluation of each individual ingredient conducted by those responsible for putting the product on the market. However, those substances for which some concern exists with respect to human health (e.g., colorants, preservatives, UV-filters, nanomaterials) are evaluated at the European Commission level by a scientific committee, curre...
Susceptibility testing of multidrug resistant Mycobacterium tuberculosis to second line 1 drugs on blood agar 2 3 4 Dilek SATANA 1 , Ahmet Yilmaz COBAN 2* , Meltem UZUN 1 5 6 7 1 Istanbul University, Istanbul Medical School, Department of Microbiology and Clinical 8 Microbiology, Đstanbul, Turkey. 9 2* Ondokuz Mayis University, Medical School, Department of Microbiology and Clinical 10 Microbio...
BACKGROUND It is well established that cardiorespiratory fitness (CRF) is inversely associated with cardiovascular and all-cause mortality. However, little is known regarding the association between CRF and incidence of heart failure (HF). METHODS AND RESULTS Between 1987 and 2014, we assessed CRF in 21 080 HF-free subjects (58.3±11 years) at the Veterans Affairs Medical Centers in Washington...
Knowledge of breed composition can be useful in multiple aspects of cattle production, and can be critical for analyzing the results of whole genome-wide association studies currently being conducted around the world. We examine the feasibility and accuracy of using genotype data from the most prevalent bovine genome-wide association studies platform, the Illumina BovineSNP50 array (Illumina In...
Cow genome sequencing is underway at Baylor College of Medicine (BCM) sequencing center and will be completed in the next few months. A recent white paper indicated a goal to identify 100,000 SNP for use in identification and mapping of QTL regions [1]. In September 2004, the preliminary assembly of the cow (Btau_1.0), Hereford breed, using whole genome shotgun (WGS) reads with an average of th...
The objective was to establish and standardise a broth microdilution susceptibility testing method for porcine Bordetella (B.) bronchiseptica. B. bronchiseptica isolates from different geographical regions and farms were genotyped by macrorestriction analysis and subsequent pulsed-field gel electrophoresis. One reference and one type strain plus two field isolates of B. bronchiseptica were chos...
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