There is a growing number of children worldwide accessing second-line anti-tuberculosis drugs for multidrug-resistant tuberculosis (TB); however, there are very few child-friendly formulations. For paediatric use, dispersible tablets offer distinct advantages over liquid formulations and other approaches. This is particularly relevant for TB, where stability, long shelf-life and reduced manufac...

INTRODUCTION Worldwide, there are approximately 8 million new cases and 3 million deaths from tuberculosis (TB) each year. TB affects the entire body and the eye. Although ocular TB is considered rare, its incidence has varied widely across time, patient populations, and geography. We report 2 patients with unique presentations of ocular TB and detail the treatment and outcome of the disease. ...

primary tuberculosis of the breast is a rare disease. it usually occurs in female of reproductive age. any form of tuberculosis mastitis may present with feature of malignancy. diagnosis is mainly based on identification of tubercle bacilli. we report a 42-year-old woman with primary tuberculosis abscess of the breast, who underwent surgical resection. fine needle biopsy failed to achieve speci...

Introduction: Tuberculosis is a chronic, highly contagious disease caused by the Bacillus Mycobacterium tuberculosis and spreads from person to through air. affects lungs majorly but also other parts of body, such as brain, intestine, spine kidney. The main cause for patient’s non-adherence anti-tuberculosis therapy ADRs varying degrees severity hepatotoxicity etc. Aim: This study aimed provide...

results results of the current study showed that the minimum inhibitory concentration value of cinnamaldehyde against m. tuberculosis was 200 µg/ml. moreover, rt-pcr data showed that a total of 25 genes were regulated by the cinnamaldehyde. of these, 12 genes were up-regulated, and 13 genes were down-regulated. conclusions cinnamaldehyde is a pattern to expand the new anti-tb drugs, because the...

This study was planned to determine HIV seroprevalence among pulmonary tuberculosis patients, to characterize the isolated mycobacteria into typical and atypical strains and to evaluate the drug resistant pattern of mycobacterial isolates. The study aims to correlate multidrug resistance (MDR) and HIV seropositivity status in pulmonary tuberculosis patients. During the year 1994-1997, 750 pulmo...

Tuberculosis is a disease as old as human history and has affected every area of human life. The struggle against tuberculosis had been started by non-governmental organizations and achieved success after second world war. In Anatolia as well as all over the world fight against tuberculosis, with the leading names in medicine, started during the Ottoman Empire. In the following years of struggl...

Lumbar vertebral tuberculosis presenting with a focal solitary osteolytic lesion is rare in spinal (TB) and the English literature describing this entity scant. The differential diagnosis includes primary secondary malignancies. In report, we describe case of 35-year-old woman who presented low back pain was found to have L4 lytic on MRI CT. Whole body CT carried out as potential malignancy sta...

introduction an unusual incidence of tuberculosis in different parts of the body is called tuberculomas. the rate of brain tuberculosis is rare. case presentation the following case of tuberculamas of the brain, presented by enhancing rings of meninges, is reported because of its rarity. it was a case of brain tuberculomas in a 15-year-old girl with primary symptoms of headache and general weak...

Efficient tuberculosis treatment requires the use of good quality medicines. The present study developed a method of dosage by High Performance Liquid Chromatography (HPLC) coupled with the dissolution of a combination of fixed doses of four anti-tuberculous (Isoniazid, Pyrazinamide, Ethambutol Hydrochlorate, Rifampicine). The elaborated protocol was thereafter used to assess the quality of med...