Information from a comprehensive drug surveillance programme is analysed to provide details of antibacterial drug use in medical wards. Some 28% of patients received antibacterial therapy, usually for the treatment of respiratory or urinary tract infections. The agents most frequently prescribed were ampicillin, co-trimoxazole and tetracyclines. Overall, 11% of recipients experienced one or mo...

Abstract Chitosan is an amorphous translucent substance with a structural unit similar to the polysaccharide structure of extracellular matrix, It has good antibacterial, biocompatible, and degradable properties. important application value in leather, water treatment, medicine, food other fields, so chitosan its modified products have received widespread attention. This article reviewed prepar...

BACKGROUND Medicinal plants play great roles in the treatment of various infectious diseases. Rhamnus prinoides is one of the medicinal plants used traditionally for treatment of bacterial diseases. The antibacterial activity of the crude extract of the plant had been shown by a previous study, but this study was undertaken to further the claimed medicinal use of the plant by screening its solv...

The aim of this study was to compare the antibacterial activity of teicoplanin and vancomycin in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) meningitis using a rabbit meningitis model. The MRSA strain ATCC 43300 was used to infect the rabbits. The vancomycin group received 20 mg/kg vancomycin every 12h (q12h), the teicoplanin group received 6 mg/kg teicoplanin q12h and t...

We proposed a strategy using nanoliposomes to protect AMPs, which improves antibacterial performance and biosafety prevents AMP enzymolysis in infected wound treatment.

BACKGROUND Bauhinia kockiana originates from Peninsular Malaysia and it is grown as a garden ornamental plant. Our previous study reported that this plant exhibited fairly strong antioxidant and antimicrobial activities. This paper focused on the assessment of the antibacterial activity of B. kockiana towards methicillin-resistance Staphylococcus aureus (MRSA), to purify and to identify the ant...

Crude extracts from eight Nigerian medicinal plants, used traditionally in the treatment of infectious and septic diseases in both humans and animals were screened in vitro for antibacterial activity, using the hole-plate diffusion method. Most of the extracts were active against gram-positive bacteria. Two of the plant, Angeiossus schimperi and Anacardium occidentale, had good antibacterial ac...

Influenza pandemics and seasonal outbreaks have shown the potential of Influenza A virus (IAV) to enhance susceptibility to a secondary infection with the bacterial pathogen Streptococcus pneumoniae (Sp). The high morbidity and mortality rate revealed the poor efficacy of antiviral drugs and vaccines to fight IAV infections. Currently, the most effective treatment for IAV is by antiviral neuram...

Peganum harmala L. (Zygophyllaceae) is one of the most famous medicinal plants used in traditional medicine of Iran. The aim of this study was to consider antibacterial effects of the methanolic extract of different parts of P. harmala including root, stem, leaf, flower and seed against some important human pathogenic bacteria. Antibacterial properties of methanolic extract of mentioned parts w...

Our objective is to evaluate the antibacterial and antioxidant activity of ethanolic extracts of Plectranthus mollis (P.mollis) and Salvia officinalis (S. officinalis) leaves locally used for treatment of microbial infection in Nilgiris of India. Antibacterial activity was determined by using agar diffusion and broth dilution methods against seven microorganisms. The antioxidant potential was a...