http://bmj.com/cgi/content/full/331/7509/155 Updated information and services can be found at: These include: Data supplement http://bmj.com/cgi/content/full/331/7509/155/DC1 "References w1 w20" References http://bmj.com/cgi/content/full/331/7509/155#otherarticles 3 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/331/7509/155#BIBL This article cites 15...

Data extraction Data were extracted on study characteristics, drug regimen, sample size, compliance, mean baseline rating on depression scales, and percentage change at end point. Treatment effects were calculated and weighted in a meta-analysis. 3 different weights were used for each treatment effect to reflect 3 different assumptions about the correlation between baseline and follow up depres...

The substituted tricyclic pyrano[2,3-e]isoindolin-3-ones and , as the core structure of stachybotrin A, B, and C (), have been regioselectively synthesized for the first time by a short route which involved Mannich reaction and Claisen rearrangement.

154 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected] International Journal of Neu...

AIM The aim of this study was to assess the prevalence and patterns of exposure to antidepressants before, during and after pregnancy in a cohort including all pregnant women in Denmark between 1997 and 2010. METHODS We performed a retrospective cohort study including 912 322 pregnancies. Information was retrieved from the Danish Birth Registry and The Register of Medicinal Product Statistics...

A facile two-step method for the construction of fused pyrrole ring leading to 5-substituted 2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-1-ones via C-C followed by intramolecular C-N bond forming reaction is described. In vitro pharmacological evaluation and molecular modelling studies of some of the compounds synthesized are presented.

Under certain conditions, groups of people may (collectively) make better judgments than experts. Galton connected this phenomenon to the phrase vox populi in a 1907 paper. Arguably, an example of the phenomenon may be found in recent stabilization of the frequency of antidepressant use, following decades of increases. There is no evidence that a change in physi-cian behaviour has caused this s...