Medicinal plants with less side effects are paramount important for humankind to cure various ailments as compared newly developed allopathic medicines. Synsepalum dulcificum Daniell, (Sapotaceae), is well known miracle fruits due its distinctive taste-modifying property. This review aimed discuss recent reported pharmacological properties and associated molecular mechanisms a novel phytotherap...

The in vitro antiradical activity of Schisandra chinensis lignans was investigated using DPPH, ABTS+, Fenton reaction inhibition and tyrosine-nitration inhibition assays, as were the in vivo antidiabetic activities of selected lignans in an animal model of alloxan-induced diabetes. Different degrees of antiradical activity were found, depending upon the structural parameters of the tested compo...

Antidiabetic and antihyperlipidemic effect of Hemidesmus indicus Linn.R.root. (HIR) was investigated in rats. Administration of HIR (40 mg/g body weight/day) for four weeks significantly decreased the serum cholesterol, triglyceride, free fatty acids and phospholipid. Four weeks treatment of diabetic rats with HIR (40 mg/g body weight/day) showed significant hypoglycemic effect. Results of the ...

Aim: Many traditional treatments have been recommended in the alternative system of medicine for treatment of diabetes mellitus. Juglans regia is one of the medicinal plants used in traditional Iranian medicine as a treatment for diabetes, but little scientific documentation supports its antidiabetic action. Th e purpose of this study was to investigate antidiabetic eff ect of J. regia leaves i...

Aloe vera gel has been claimed to have antidiabetic activity but not all published results are consistent. We investigated the effect of oral administration of one tablespoonful of Aloe vera juice, twice a day for at least 2 weeks in patients with diabetes. Blood sugar and triglyceride levels in the treated group fell; cholesterol levels were not affected. The results suggest the potential of a...

This study is aimed at assessing the inhibitory effect of teas on key enzymes (α-amylase and α-glucosidase) linked with type-2 diabetes and their antioxidant properties. Four samples of three brands were used; infusions of green tea (GT), 2 brands of black tea (BT), and a formulated herbal preparation for diabetes (ADT) (white tea, Radix Puerariae, Radix ophiopogonis, hawthorn berry, Chinese ya...

Polyherbal extract which consists of ethanolic extract of MadhucaLatifolia, AristolochiaBracteata, AristolochiaIndica was investigated for its possible antidiabetic effect in alloxan-induced diabetic rats and to assess the synergistic activity of three plants. The animals were grouped into four six animals each. The first group received normal saline solution(0.9% sodium chloride), which was us...

Diabetes mellitus is the most common metabolic disorder affecting millions worldwide. It is recognized as a global major health problem. As alternatives to the available orthodox medicines, plants are considered a potential source for the treatment of diabetes within traditional ethnomedicine practices. In the Jordanian traditional medicine a significant selection of ethnobotanicals is promoted...

The thiazolidinedione class peroxisome proliferator-activated receptor gamma (PPARγ) agonists are restricted in clinical use as antidiabetic agents because of side effects such as edema, weight gain, and heart failure. The single and selective agonism of PPARγ is the main cause of these side effects. Multitargeted PPARα/γ/δ pan agonist development is the hot topic in the antidiabetic drug resea...

The aim of this research was to investigate antidiabetic activity of Costus igneus (also known as insulin plant) leaves extracts in streptozotocin induced diabetic albino rats. A comparison was made between the action of Costus igneus extract and a known antidiabetic drug glibenclamide (5mg/kg body wt.). An oral glucose tolerance test (OGTT) was also performed in experimental diabetic rats. Eth...