Methanol extract of Muntingia calabura L. (family Muntingiaceae) leaf has been reported to exert various pharmacological activities including hepatoprotection. The present study was carried out to identify the most effective hepatoprotective partition derived from the extract and to determine the mechanisms of action involved. The extract was partitioned using solvents with different polarity t...

iron is a pro-oxidant cofactor that may be linked to atherosclerosis progression. free iron catalyzes the generation of free radicals and free radicals promote the oxidation of lipids. reduction of body iron stores secondary to blood donation has been hypothesized to reduce lipid peroxidation. the aim of this study was to evaluate the association between blood donation and antioxidant enzymes a...

The free radicals produced during the cellular oxidation and metabolic processes cause excessive damage to biomembranes and macromolecules like DNA, carbohydrates, lipids and proteins. Such a condition of oxidative stress and the harmful effects of free radicals bring about imbalance in the antioxidant system of the human body. The pathological conditions so developed are implicated into many d...

the effect of salinity was assessed on the activity of some major antioxidant enzymes i.e., superoxide dismutase (sod), peroxidase (pod), catalase (cat), in the seedlings’ roots or shoots of three winter canola (brassica napus l.) cultivars, colvert (tolerant), symbol (semi tolerant) and agat (susceptible). seedlings were treated with 0 (control), 50, 100 and 150 mm nacl for 24 h in hydropoic c...

Objective: The present study was conducted to investigate the antioxidant and hepatoprotective activity of the hydro-alcoholic extract of aerial parts of Artemisia dracunculus (HAAD) against CCl4-induced hepatotoxicity in rats. Materials and Methods: The antioxidant activity was evaluated by reducing power, 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 20-azino-bis (3-ethylbenzothiazoline-6-sulf...

Deinococcus radiodurans shows remarkable resistance to reactive oxygen species (ROS), generated by irradiation. Disruption of recX (dr1310) in D. radiodurans using targeted mutagenesis method enhanced its ROS scavenging activity, and recX overexpression in this bacterium repressed its antioxidant activity significantly. Further analyses on catalase and superoxide dismutase, two important antiox...

Background: The herb feverfew (Tanacetum parthenium L., Asteraceae) has an ancient reputation as an effective anti-inflammatory, analgesic, antipyretic, and anti-asthmatic agent. Parthenolide a gemacranolide-type sesquiterpene lactone is the major constituent of European feverfew. Materials and Methods: The present study was intended to evaluate the in vivo antioxidant potential and radioprotec...