نتایج جستجو برای: antiplatelet therapy

تعداد نتایج: 658043  

Journal: :Cardiovascular Pharmacology: Open Access 2014

Journal: :Circulation: Cardiovascular Interventions 2012

Journal: :Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2007
Cindy L Grines Robert O Bonow Donald E Casey Timothy J Gardner Peter B Lockhart David J Moliterno Patrick O'Gara Patrick Whitlow

Dual antiplatelet therapy with aspirin and a thienopyridine has been shown to reduce cardiac events after coronary stenting. However, many patients and healthcare providers prematurely discontinue dual antiplatelet therapy, which greatly increases the risk of stent thrombosis, myocardial infarction, and death. This advisory stresses the importance of 12 months of dual antiplatelet therapy after...

2013
R Habekovic M Dubravec D Zigrovic S Gorupec-Kurtanjek L Curak V Berkovic D Crnkovoic S Beric M Petricevic B Biocina

Background Hemostatic disorder and massive bleeding are common complications after cardiac surgery procedures, particularly in procedures requiring prolonged cardiopulmonary bypass. Conventional laboratory coagulation tests failed to predict hemostatic disorder and consequent proclivity to excessive bleeding. On the other hand there is evergrowing proportion of patients who need antiplatelet th...

Journal: :Stroke 2014
Emer R McGrath Moira K Kapral Jiming Fang John W Eikelboom Aengus ó Conghaile Michelle Canavan Martin J O'Donnell

BACKGROUND AND PURPOSE For patients with atrial fibrillation and ischemic stroke (IS), current guidelines recommend oral anticoagulation (OAC) alone for secondary prevention of IS. In a large prospective cohort of patients with acute IS and atrial fibrillation, we determine the association between antithrombotic regimen on discharge and risk of major vascular events. METHODS Prospective cohor...

Aspirin is an irreversible and non-selective inhibitor of cyclo-oxygenase. It represents the cornerstone of antiplatelet therapy and is used in secondary prevention of cardiovascular disease. Disagreement over the optimal maintenance dosage still exists; in America and Europe the most used doses of aspirin are 81 mg and 100 mg daily, respectively. There is also debate on the formulation and rou...

2007
Cindy L. Grines

Dual antiplatelet therapy with aspirin and a thienopyridine has been shown to reduce cardiac events after coronary stenting. However, many patients and healthcare providers prematurely discontinue dual antiplatelet therapy, which greatly increases the risk of stent thrombosis, myocardial infarction, and death. This advisory stresses the importance of 12 months of dual antiplatelet therapy after...

Journal: :Pharmacotherapy 2012
Emily S Reese C Daniel Mullins Amber L Beitelshees Eberechukwu Onukwugha

STUDY OBJECTIVE To estimate the cost-effectiveness of genotype-guided selection of antiplatelet therapy compared with selecting clopidogrel or prasugrel irrespective of genotype. DESIGN Decision model based on event occurrence in the Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition with Prasugrel-Thrombolysis in Myocardial Infarction (TRITON-TIMI) 38. PA...

2012
Hung Yi Chen

Stent thrombosis is rare but can lead to potential severe consequence. The incidence is relative higher in drug-eluting sent than bare-metal stent implantation. Dual antiplatelet therapy is the major treatment to avoid early and late stent thrombosis. Simultaneous two stents thrombosis is rare. Although mechanical or/and procedure factors may predispose to stent thrombosis occurred, simultaneou...

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