نتایج جستجو برای: antithrombin iii

تعداد نتایج: 260296  

Journal: :Blood 2012
Aisha Bruce M Patricia Massicotte

In this issue of Blood, Holzhauer et al have determined a novel method of identifying patients with protein C, protein S, and antithrombin deficiency who are at increased risk of developing venous thromboembolism (VTE; see figure). Children with VTE and their relatives were screened for inherited thrombophilia including proteins C and S and antithrombin deficiency; and Factor (F)V G1691A and FI...

Journal: :Circulation research 1977
S N Gitel S Wessler V M Medina

When activated factor X (Xa) inhibitory activity of serially diluted human and rabbit plasma is determined in a low salt assay, a lineare plot is obtained for human, but not for rabbit plasma. When a high salt assay is used, the dilution curves for both human and rabbit plasma are linear, and qualititive as well as quantitative differences are essentially eliminated. On Sephadex G-200 chromatog...

Journal: :Clinical chemistry and laboratory medicine 2014
Emmanuel J Favaloro

There has been increasing recognition of various laboratory markers of thrombophilia that are associated with increased risk of thrombosis either through hereditary (especially Factor V Leiden, prothrombin G20210A mutation, and protein C, S and antithrombin deficiencies) and/or acquired means (e.g., antiphospholipid antibodies) over past decades. This has led to an explosion of clinical request...

2017
Praveen Papareddy Martina Kalle Ravi KV Bhongir Matthias Mörgelin Martin Malmsten Artur Schmidtchen

Antithrombin III (ATIII) is a key antiproteinase involved in blood coagulation. Previous investigations have shown that ATIII is degraded by Staphylococcus aureus V8 protease, leading to release of heparin binding fragments derived from its D helix. As heparin binding and antimicrobial activity of peptides frequently overlap, we here set out to explore possible antibacterial effects of intact a...

Journal: :Clinical chemistry and laboratory medicine 2014
Massimo Franchini

In the past decades, the recognition of several inherited thrombophilic traits has greatly improved our knowledge of the pathogenesis of venous thromboembolism, explaining about half of all idiopathic cases. As a consequence, thrombophilia testing has enormously increased in the past years for various clinical conditions. In this paper, the current indications of the most commonly tested thromb...

2011
B Beltran H Bichsel B Cai G A Cox H Deng J Detwiler J A Formaggio S Habib A L Hallin A Hime M Huang C Kraus H R Leslie J C Loach R Martin S McGee M L Miller B Monreal J Monroe N S Oblath S J M Peeters A W P Poon G Prior K Rielage R G H Robertson M W E Smith L C Stonehill N Tolich T Van Wechel H Wan Chan Tseung J Wendland J F Wilkerson

The third phase of the Sudbury Neutrino Observatory (SNO) experiment added an array of 3He proportional counters to the detector. The purpose of this neutral-current detection (NCD) array was to observe neutrons resulting from neutral-current solar-neutrino–deuteron interactions. We have developed a detailed simulation of current pulses from NCD array proportional counters, from the primary neu...

2004
A. Bellerive

This paper reviews the constraints imposed on the solar neutrino mixing parameters by data collected by the Sudbury Neutrino Observatory (SNO). The SNO multivariate analysis is reviewed. The global solar neutrino analysis is emphasized in terms of matter-enhanced oscillation of two active flavors. An outline of how SNO uses the data to produce oscillation contour plots and how to include the re...

2007
Philip Lewis Tristan Quaife Alice Holt

18.2.1 Model Development within SDGVM The primary Dynamic Global Vegetation Model (DGVM) for estimating that we are making use of for flux estimation is the Sheffield DGVM (SDGVM). This year’s major SDGVM model developments have been concerned with tracing the dynamics of individual functional type cohorts and a completely new representation of root and soil carbon dynamics. Of particular relev...

Journal: :Blood 1966
H H Henstell M Kligerman

By HENRY II. IIENSTELL AN!) MIRIAM KLICERMAN T COMMUNICATION is concerned with a systematic study of pr gressive antithrombic activity. The results imidicate that amititlirombic activity is not due to a single entity but consists of a three-phase system: a plasma antithrombin which appears to be identical with Antithrombin III, a plasma inhibitor which neutralizes the plasma antithrombin, and a...

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