We previously demonstrated that truncated desmoplakin I (DP I) molecules containing the carboxyl terminus specifically coalign with and disrupt both keratin and vimentin intermediate filament (IF) networks when overexpressed in tissue culture cells (Stappenbeck, T. S., and K. J. Green. J. Cell Biol. 116:1197-1209). These experiments suggested that the DP carboxyl-terminal domain is involved eit...

plants firing fuel oil produce huge quantities of fly ash as solid waste, which needs to becharacterized prior to its proper management. it is worth mentioning that the published literature lackcomprehensive information on the characteristics of such fly ash. characteristics of fuel oil fly ash producedat selected power (pp) and water desalination (dp) plants were determined. the results showed...

In this paper I show that there are clause-like NP-movements within the DP. There have been various proposals for N-movement within the DP (Bernstein 1993, Longobardi 1994 etc.) but none concerning NP-movement. I show that in Bangla (Bengali) at least two types of DP-internal NP movements take place, both of which are due to specificity. The analysis offered, in terms of a difference between nP...

background: noise-induced hearing loss (nihl) is one of the most common occupational illnesses. most of the studies on nihl were conducted at high noise levels that people are rarely exposed to but in industries. the function of the outer hair cells (ohcs) is impaired after exposure to industrial noise. distortion product otoacoustic emissions (dpoaes) are useful in examination of noise-induced...

in his insightful editorial, nir eyal explores the connections between nudging and shaming. one upshot of his argument is that we should question the principle of the least restrictive alternative in public health and health policy. in this commentary, i maintain that eyal’s argument undermines only a rather implausible version of the principle of the least restrictive alternative and i sketch ...

For any connected graph G $G$ , let P ( m ) $P(G,m)$ and D ${P}_{DP}(G,m)$ denote the chromatic polynomial Dvořák Postle (DP) color function of respectively. It is known that ≤ ${P}_{DP}(G,m)\le P(G,m)$ holds for every positive integer $m$ . Let ≈ $D{P}_{\approx }$ (resp., < $D{P}_{\lt be set graphs which there exists an M $M$ such = ${P}_{DP}(G,m)=P(G,m)$ ${P}_{DP}(G,m)\lt all integers ≥ $m\ge...

This paper compares two optimal energy management methods for parallel hybrid electric vehicles using an Automatic Manual Transmission (AMT). A control-oriented model of the powertrain and vehicle dynamics is built first. The energy management is formulated as a typical optimal control problem to trade off the fuel consumption and gear shifting frequency under admissible constraints. The Dynami...

Shi and Tsai (JRSSB, 2002) proposed an interesting residual information criterion (RIC) for model selection in regression. Their RIC was motivated by the principle of minimizing the Kullback-Leibler discrepancy between the residual likelihoods of the true and candidate model. We show, however, under this principle, RIC would always choose the full (saturated) model. The residual likelihood ther...

In this paper we propose and analyse a choice of parameters in the multi-penalty regularization. A modified discrepancy principle is presented within the multi-parameter regularization framework. An order optimal error bound is obtained under standard smoothness assumptions. We also propose a numerical realization of the multi-parameter discrepancy principle based on the model function approxim...

The \L{curve" is a plot (in ordinary or doubly{logarithmic scale) of the norm of (Tikhonov{) regularized solutions of an ill{posed problem versus the norm of the residuals. We show that the popular criterion of choosing the parameter corresponding to the point with maximal curvature of the L{curve does not yield a convergent regularization strategy to solve the ill{posed problem. Nevertheless, ...