Numerous members of the Anthemideae tribe are important as cut flowers and ornamental crops, as well as being medicinal and aromatic plants, many of which produce essential oils used in folk and modern medicine and in the cosmetics and pharmaceutical industry. Essential oils generally have a broad spectrum of bioactivity, owing to the presence of several active ingredients that work through var...

The work in this thesis was carried out in the context of the Artemisia project supported by PROGRESS/STW.

BACKGROUND The use of antioxidants in the treatment of infertility has been suggested and recent studies have indicated that oral administration of Satureja Khuzestanica essential oil (SKEO) to rats induces significant antioxidative effects. OBJECTIVE This systematic review was conducted to evaluate the effectiveness of antioxidants in infertility and also to assess the effectiveness of Satur...

the formation of hemozoin (malaria pigment) has been proposed as an ideal drug target for antimalarial screening programs. in this study, we used an improved, cost-effective and high-throughput spectrophotometric assay to screen plant extracts for finding novel antimalarial plant sources. fifteen extracts with different polarity from three iranian artemisia species, a. ciniformis, a. biennis an...

The title compound, C(17)H(16)O(6), was isolated from the Chinese Tibetan medicinal plant Artemisia sphaerocephala Kraschen. The mol-ecular conformation is consolidated by two intra-molecular O-H⋯O hydrogen bonds. A further inter-molecular O-H⋯O hydrogen bond leads to chains along [010] in the crystal structure.

Two effective cytochrome P450 (CYP) inhibitors were isolated from tarragon, Artemisia dracunculus. Their structures were spectroscopically identified as 2E,4E-undeca-2,4-diene-8,10-diynoic acid isobutylamide (1) and 2E,4E-undeca-2,4-diene-8,10-diynoic acid piperidide (2). Both compounds had dose-dependent inhibitory effects on CYP3A4 activity with IC50 values of 10.0 ± 1.3 µM for compound 1 and...

A combination of solid-phase-extraction (SPE) and reversed-phase preparative high-performance liquid chromatography (prep-HPLC) of the methanolic extract of the aerial parts of Artemisia splendens (common name: “Asia Minor Wormwood”), an endemic Iranian species, afforded Zand E-melilotosides (1 and 2), Zand E-4-methoxy-melilotosides (3 and 4), and a new dimer, bis-ortho-Z-melilotoside (5, named...

Artemisia species, widespread in nature, are frequently utilized for the treatment of diseases such as malaria, hepatitis, cancer, inflammation, and infections by fungi, bacteria, and viruses. Furthermore, some Artemisia constituents were found to be potential insecticides and allelopathic chemicals. This genus is receiving growing attention presumably due to: (i) the diversified biology and ch...