BACKGROUND AND PURPOSE Independently assessed data on frequency, severity, and determinants of neurological deficits after endovascular treatment of brain arteriovenous malformations (AVMs) are scarce. METHODS From the prospective Columbia AVM Study Project, 233 consecutive patients with brain AVM receiving > or =1 endovascular treatments were analyzed. Neurological impairment was assessed by...

BACKGROUND AND PURPOSE To evaluate the hemorrhage rates of cerebral arteriovenous malformations (AVM) and the risk factors of hemorrhage before and after Gamma Knife radiosurgery (GKS). METHODS The annual hemorrhage rate was calculated as the number of hemorrhages divided by the patient-years at risk. Characteristics of patients and AVM related to hemorrhagic or nonhemorrhagic presentation we...

BACKGROUND AND PURPOSE The role of abnormal angiogenesis in the formation and progression of cerebral arteriovenous malformations (AVMs) is unclear. Previous studies have demonstrated increased local expression of vascular endothelial growth factor (VEGF) in AVM tissue and increased circulating levels of VEGF in AVM patients. We sought to further investigate the role of VEGF in AVM pathophysiol...

BACKGROUND AND PURPOSE We sought to assess the relative risk of hemorrhagic presentation of brain arteriovenous malformations (AVMs) located in the arterial borderzone territories. METHODS The 464 consecutive, prospectively enrolled patients from the New York AVM Databank were analyzed. AVM borderzone location was coded positive when the malformation was supplied by branches of at least 2 of ...

BACKGROUND Arteriovenous malformations (AVM) markedly alter the distribution of the regional cerebral blood flow, as they consist of abnormal arteries and veins with no resistance vessels between them. The aim of this study was to the evaluate diagnostic utility of cerebral perfusion scintigraphy (dynamic phase and SPECT) in patients with AVM. MATERIAL AND METHODS Nineteen patients were exami...

The long-term outcomes of gamma knife surgery (GKS) in patients with posterior fossa arteriovenous malformations (AVMs) were retrospectively analyzed in 82 patients followed up for more than 5 years to evaluate the efficacy and safety. The median AVM volume at GKS was 0.95 cm(3). The prescribed dose to the AVM margin was median 18 Gy with 1-18 isocenters. The actual complete AVM obliteration ra...

A 67-year-old man with a history of melena and a hemoglobin level of 4.8g/dL was referred to our center for endoscopic evaluation. He had no significant comorbidities and his liver and renal functions were normal. His anemia was corrected with multiple blood transfusions. As upper gastrointestinal endoscopy showed fresh blood in the second part of the duodenum, a side-viewing endoscopy was carr...

Arteriovenous malformations (AVMs) are the major cause of haemorrhagic stroke in young adults, but the causal factors leading to AVM formation are unknown. An important clue is provided by the familial human disease Hereditary Haemorrhagic Telangiectasia (HHT), which is characterised by multi-organ AVMs and bleeding. HHT is inherited in an autosomal dominant manner and most patients carry mutat...

Brain Arteriovenous malformations (AVM) are abnormal communication between parts of cranial arterial and venous systems with the lack of a true nutritive and absorptive capillary bed [1]. The universal prevalence of AVM is relatively uncommon, with a prevalence ranging from 0.01-0.5%, 10/100000 to 140500/100000 specifically [2-7] clustering between 3rd and 5th decade i.e. presenting usually bef...

Arteriovenous malformations (AVMs) are the major cause of haemorrhagic stroke in young adults, but the causal factors leading to AVM formation are unknown. An important clue is provided by the familial human disease Hereditary Haemorrhagic Telangiectasia (HHT), which is characterised by multi-organ AVMs and bleeding. HHT is inherited in an autosomal dominant manner and most patients carry mutat...