Ocular involvement in patients with chronic myelomonocytic leukemia (CMML) is rarely reported, owing in part to the fact that the severe illness faced by many of these patients limits the feasibility of ocular examinations. Nevertheless, post-mortem examination of eyes from patients without ophthalmological symptoms and diagnosis of CMML has revealed ocular infiltration of atypical cells. We pr...

AIM/PURPOSE To present a summary of 10 cases of non-arteritic anterior ischemic optic neuropathy (NAION) in patients who received phosphodiesterase type 5 (PDE-5) inhibitors. METHODS A case series of 10 patients who, after regular intake of Sildenafil, presented with a first episode of NAION in one eye. NAION was diagnosed based on the following criteria: acute, painless, unilateral loss of v...

Purpose To report a case of bilateral central retinal artery occlusion with both anterior and posterior ischemic optic neuropathy. Observations A 65-year-old Caucasian woman presented with acute respiratory distress syndrome and septic shock. After treatment with vasopressors and prolonged prone positioning, she was noted to be bilaterally completely blind on hospitalization day 12. Evaluatio...

BACKGROUND The incidence of anterior ischemic optic neuropathy after coronary artery bypass graft procedures ranges from 1.3 to 0.25%. The mechanisms of anterior ischemic optic neuropathy after cardiovascular procedures remain undefined but many systemic and related-to-surgery risk factors could underlie anterior ischemic optic neuropathy. In this case, we report a rare presentation of a bilate...

purpose : to evaluate the effects of memantine on improving visual function in patients with acute nonarteritic anterior ischemic optic neuropathy (naion) methods : this was a prospective, double masked, randomized, clinical trial. the study involved 47 subjects with unilateral naion of less than 8 weeks duration. eligible patients were randomly allocated to take either memantine tablets (5 mg ...

PURPOSE To investigate the differences in retinal nerve fiber layer (RNFL) change and optic nerve head parameters between non-arteritic anterior ischemic optic neuropathy (NAION) and open angle glaucoma (OAG) with altitudinal visual field defect. METHODS Seventeen NAION patients and 26 OAG patients were enrolled prospectively. The standard visual field indices (mean deviation, pattern standar...