An unprecedented base-promoted direct olefination of aryl alcohols with sulfones via a Julia-type reaction has been described. No extra reductants are needed for Julia reaction since alcohols work as double sources of aldehydes and the hydride. Generally high yields were given for both terminal and highly (E)-selective internal olefins.

A slight excess of silyl trifluoromethanesulfonate mediates a tandem enol silane formation-Mukaiyama aldol reaction in the presence of Hunig’s base. Preformation of the enol silane is unnecessary for efficient reactions, which proceed in 75-97% yield for the addition of aryl methyl ketones and acetate esters to non-enolizable aldehydes. Mechanistic data suggests that free amine is crucial for f...

In the absence of any additional catalysts, the reactions of (CF(3)SO)(2)CH(2), aldehydes, and 1,3-dienes gave gem-bis(triflyl)cyclohexenes in excellent yields with high regioselectivity. gem-Bis(triflyl)cyclohexene products can be easily converted to the corresponding aryl trifluoromethyl sulfones.

an efficient one-pot condensation for the synthesis of 1,8-dioxo-octahydroxanthene is  achieved through a condensation of aryl aldehydes and 5,5-dimethyl-1,3-cyclohexandione in the presence of  nbs. this method enjoys several advantages such as low cost, simple work up procedure and safe reaction condition. in addition, water was chosen as a green solvent.

reaction between aromatic aldehydes and 3–methyl-1-phenyl-2-pyrazoline-5-one catalyzed by nano-sio2/hclo4 in water under reflux provided a simple and efficient route for the synthesis of 4-((5-hydroxy-3-methyl-1-phenyl-1h-pyrazol-4-yl)(aryl)methyl)-3-methyl-1-phenyl-1h-pyrazol-5-ol derivatives in high yields.

A convenient, efficient and practical procedure for the synthesis of 1-amidoalkyl 2-naphthols is described by condensation of aromatic aldehydes with amides and 2-naphthol in the presence of P2O5/SiO2 as an efficient catalyst. Moreover, in the present of this catalyst, the synthesis of 14-aryl or alkyl-14H-dibenzo[a,j]xanthenes is studied by co...

P2O5-SiO2 (30% w/w) was found to be a useful catalyst for the synthesis of various 2-substituted aryl benzimidazoles under solvent-less and in solvent conditions from o-phenylenediamine and aldehydes. The products were directly recrystallized from methanol.

P2O5-SiO2 (30% w/w) was found to be a useful catalyst for the synthesis of various 2-substituted aryl benzimidazoles under solvent-less and in solvent conditions from o-phenylenediamine and aldehydes. The products were directly recrystallized from methanol.

By using [RuCl2(p-Cymene)]2/Cs2CO3 as an efficient catalyst system, the readily available, inexpensive aryl methanols were firstly employed for dehydrogenative synthesis of aryl substituted 1,3,5-triazine derivatives. Due to the inherent stability of alcohols in contrast with aldehydes, our synthetic protocol is adaptable to a broad substrate scope, there is no need for stringent protection dur...

We hereby report a mild and efficient coupling reaction between alkyl aldehydes and aryl diamines. In the presence of a Cu(2+) or a Zn(2+) ion, oxygen (O2) in air is able to promote the oxidative condensation of the two readily preparable functional groups, forming stable benzimidazole linkages in neutral aqueous solution at room temperature (RT). We demonstrated that the reaction could be util...