We read with great interest the article ‘Mean Platelet Volume is a useful indicator of systemic inflammation in cirrhotic patients with ascitic fluid infection’ by Suvak, et al.1 The authors concluded that MPV is increased in cirrhotic patients with ascitic fluid infection (AFI) and MPV may be a predictive test in predicting AFI. We would like to thank the authors for their valuable contributio...

The leaves of Chenopodium ambrosioides L. [Chenopodiaceae] ('mastruz') have been indicated for the treatment of several diseases, among which the cancer. There are no results focusing the effect of C. ambrosioides treatment on tumor development in vivo. The aim of this study was to investigate the effect of treatment with C. ambrosioides on Ehrlich tumor development. Swiss mice were treated by ...

For a number of years our investigations of Ehrlich ascites tumor (EAT) in Mus musculus as a model for tumor immunity studies have yielded variable LD50 values. To explain these results, the hypothesis that the cell challenge is modified during transfer of the stock cells from animal to animal is being tested. Our first attempts at freezing a stock cell suspension of EAT in the ascitic fluid or...

PURPOSE Monoclonal antibodies or specific antibodies are now an essential tool of biomedical research and are of great commercial and medical value. The purpose of this study was to produce large scale of monoclonal antibody against CD34 in order to diagnostic application in leukemia and purification of human hematopoietic stem/progenitor cells. METHODS For large scale production of monoclona...

An 81-year old woman with a history of chronic lymphocytic leukemia (CLL) was admitted with night sweats and abdominal distension. A complete blood count showed hemoglobin 5 g/dL, white blood cell (WBC) count 28.5¥109/L and platelets 38.4¥109/L. Peripheral blood smear examination showed a large number of smudge cells and lymphocytosis composed of mature-looking lymphocytes with clumped nuclear ...

The role of contaminated preservation fluid in the development of infection after liver transplantation has not been fully elucidated. To assess the incidence and etiology of contaminated preservation fluid and determine its impact on the subsequent development of infection after liver transplantation, we prospectively studied 50 consecutive liver transplants, and cultured the following samples...

Laminin levels in ascitic fluid have been proposed as a marker for neoplastic ascites. We compared the concentration of laminin in serum and in ascitic fluid from patients with hepatic cirrhosis and peritoneal carcinomatosis and assessed the diagnostic value of serum laminin levels in differentiating neoplastic from benign ascites. Laminin concentrations were determined by ELISA with antibodies...

BACKGROUND AND AIMS Translocation of intestinal bacteria to ascitic fluid is probably the first step in the development of episodes of spontaneous bacterial peritonitis in patients with cirrhosis. We have recently reported the detection of bacterial DNA in blood and ascitic fluid from patients with advanced cirrhosis, what we consider as molecular evidence of bacterial translocation. Several st...

The action of human ascitic fluid and of dog serum on the immunization of fibroblasts in vitro was investigated. The toxic effect of ascitic fluid upon fibroblasts was slight, while that of dog serum was marked. When a small amount of antigen (1.5 to 2 per cent dog serum, or 8 per cent ascitic fluid) was present in the medium, the resistance of the fibroblasts slowly increased, reached its maxi...

Nanomedicine concerns the use of precision-engineered nanomaterials to develop novel therapeutic and diagnostic modalities for human use. The present study demonstrates the efficacy of biologically synthesized silver nanoparticles (AgNPs) as an antitumor agent using Dalton's lymphoma ascites (DLA) cell lines in vitro and in vivo. The AgNPs showed dose- dependent cytotoxicity against DLA cells t...