Perinatal hypoxia results in neuronal and endothelial cell damage. The main purpose of this study was to investigate the correlation of soluble intercellular adhesion molecule 1 (sICAM-1) expression and peripheral blood changes in perinatal asphyxia with neuronal injury markers in low birth weight (LBW) neonates. We compared the concentrations of serum sICAM-1, neuron-specific enolase (NSE) and...

BACKGROUND Birth asphyxia is one of the commonest causes of neonatal morbidity and mortality in developing countries. Together with prematurity and neonatal sepsis, they account for over 80% of neonatal deaths. AIM To determine the incidence and mortality rate of birth asphyxia in Warri Niger Delta of Nigeria. MATERIALS AND METHOD Recovery of case notes of all the newborn babies seen from J...

Hypoxic ischemic encephalopathy after perinatal asphyxia is a major cause of mortality and morbidity in infants. Here, we evaluated pathologic changes in the hippocampi of a cohort of 16 deceased full-term asphyxiated infants who died from January 2000 to January 2009. Histochemical and immunocytochemical results for glial and neuronal cells were compared between cases with or without seizures ...

background: perinatal asphyxia is a common cause of infant morbidity and mortality and long-term neurological disabilities. due to the high costs of admission, a large proportion of births and neonatal deaths occur in non-hospital settings. this study aimed to evaluate the incidence rate of perinatal asphyxia before and after the implementation of the health improvement program. methods: this d...

OBJECTIVE To test the hypothesis that acute kidney injury (AKI) would be independently associated with increased morbidity and mortality. STUDY DESIGN A total of 96 consecutively cooled infants were reviewed retrospectively. Modified Acute Kidney Injury Network criteria were used to classify AKI based on absolute rise in serum creatinine (SCr) level from a previous trough (stage I, rise in SC...

Objectives : To study the cord blood nucleated RBC count (NRBC) in asphyxiated and nonasphyxiated fetuses at birth and to find out the correlation between NRBC count, fetal acidosis and the clinical markers of asphyxia. Methods : This is a prospective comparative study conducted between 2002 and 2004. Parturient women who were in labor between 37 and 42 weeks of gestation were selected after sa...

OBJECTIVE Therapeutic hypothermia has become a standard neuroprotective treatment in term newborn infants following perinatal asphyxia. Active cooling with whole body surface or head cooling is complex, expensive and often associated with initial hypothermic overshoot. We speculated that passive cooling might suffice to induce and maintain hypothermia. METHODS We analysed 18 asphyxiated term ...

Received Aug 26, 2017 Revised Nov 2, 2017 Accepted Nov 20, 2017 An investigation into optimized support vector machine (SVM) integrated with principal component analysis (PCA) and orthogonal least square (OLS) in classifying asphyxiated infant cry was performed in this study. Three approaches were used in the classification; SVM, PCA-SVM, and OLSSVM. Various numbers of features extracted from M...