BACKGROUND It is well known that, stemming from the mutual interplay between chromophores, circular dichroism (CD) is a powerful technique to deal with structural problems for both the small organic molecule and the biopolymer. However, quantitative interpretations of the spectroscopic and structural terms that give rise to the exciton couplet are usually presented for ideal cases, or a few CD ...

ConspectusContradictory to the first intuitive impression that forging putatively flat aromatic rings evades stereoisomerism, a striking variety of atropisomeric compounds are conceivable by formation arenes, offering captivating avenues for catalyst-controlled stereoselective strategies. Since assembled products contain one or several rotationally restricted single bonds characterized especial...

BACKGROUND Recently, the discovery of the elansolids, a group of macrolides, was reported. The molecules show activity against methicillin-resistant Staphylococcus aureus as well as other gram-positive organisms. This fact renders those substances a promising starting point for future chemical development. The active atropisomers A1/A2 are formed by macrolactonization of the biosynthesis produc...

In this paper, we review contaminants in bowhead whale tissues. Mean concentrations of metals (As, Cd, Co, Cu, Pb, Mg, Mn, Hg, Mo, Se, Ag, and Zn) studied in bowhead whale liver, blubber, epidermis, muscle, and kidney are low or normal compared to most mysticete species. From a consumption or subsistence perspective the kidney represents a source of cadmium (Cd) requiring further scrutiny, whil...