OBJECTIVE To determine the prevalence, impact, and stability of different subtypes of headache in a 30 year prospective follow-up study of a general population sample. DESIGN Prospective cohort study. SETTING Canton of Zurich, Switzerland. PARTICIPANTS 591 people aged 19-20 from a cohort of 4547 residents of Zurich, Switzerland, interviewed seven times across 30 years of follow-up. MAIN...

OBJECTIVES To examine the association between migraine and migraine aura status with risk of haemorrhagic stroke. DESIGN Prospective cohort study. SETTING Women's Health Study, United States. PARTICIPANTS 27,860 women aged >or=45 who were free from stroke or other major disease at baseline and had provided information on self reported migraine, aura status, and lipid values. MAIN OUTCOM...

Magnesium sulphate has been used in the acute treatment of migraines; some studies found it to be a highly effective medication in the acute control of migraine pain and associated symptoms. This randomized, double-blind, placebo-controlled study assesses the effect of magnesium sulphate on the pain and associated symptoms in patients with migraine without aura and migraine with aura. Sixty pat...

AURA is an AI-motivated system with a healthy intersection with the sciences: its short-term goal is to enable domain experts to construct declarative knowledge bases (KBs) from 50 pages of a science textbook for Physics, Chemistry, and Biology in a way that another user can pose questions similar to those in an Advanced Placement (AP) exam and get answers and explanations. In building AURA, an...

CONTEXT Migraine is considered to be an episodic condition with no long-term consequences. However, recent studies suggest that migraine attacks may be associated with pathologic changes in the brain, particularly in the cerebellum. OBJECTIVE To determine whether individuals not reporting headache compared with individuals reporting migraine symptoms, particularly aura, in midlife are at incr...

Conflicting data on cognitive defects in migraine could be explained by differences in the clinical variables of the populations studied. We investigated 21 patients with migraine with aura and 24 with migraine without aura, diagnosed according to the International Headache Society criteria. The patients were submitted to a comprehensive battery of neuropsychological tests and grouped according...

Patients with migraine with aura often experience a variety of visual and somatosensory phenomena and disturbances of higher cortical functions. Analysis of these alterations may provide important information about the involvement of different cortical regions in cortical spreading depression (CSD). We report five cases of migraineurs who experience unusually abundant clinical phenomena during ...

P/Q Ca2+ channels are genetically abnormal in most cases of familial hemiplegic migraine (FHM) and may be involved in other types of migraine. They are also found at the neuromuscular junctions, where they control stimulation-induced acetylcholine release. Prolonged aura is a very frequent clinical feature in FHM patients. The objective of this study was thus to explore neuromuscular transmissi...

Background and Purpose The aura phase of migraine is associated with focal blood flow changes, but it has been largely unknown whether these changes are correlated to changes in the cerebral metabolism. Methods Eight patients required carotid angiography for evaluation of transient neurological attacks. Cerebral blood flow (CBF) results, angiography, and clinical observations subsequently sugge...

Aura típica é uma experiência sensorial de curta duração que surge antes ou durante a crise de enxaqueca e é experimentada por cerca de 1/4 de todos os pacientes com enxaqueca. A experiência pode ser visual, sensitiva, ou resultar em problemas com a fala ou dificuldade em lembrar a palavra certa durante uma conversação. As alterações visuais típicas são visão de manchas, perturbações visuais em...