Celiac disease has been associated with other autoimmune disorders such as autoimmune hepatitis, moreover it is known that T cell mediated immune response to dietary gluten and released cytokines are important for the entheropathy seen in celiac disease. We investigated celiac autoantibodies in patients with autoimmune hepatitis (AIH), and chronic hepatitis B (CHB).Sera from 84 patients with Au...

Whither smooth muscle antibodies in the third millennium? Lupoid hepatitis (now known as autoimmune hepatitis type I) was defined as an autoimmune disease by Mackay and colleagues in 1965. 1 An immunological marker of the disease was identified by Johnson et al in 1965 in the form of an " antismooth muscle antibody ". 2 3 Over the following 30 years, smooth muscle antibody (SMA) has been used i...

Multiple sclerosis (MS) is an autoimmune, inflammatory disease characterized by demyelination and axonal degeneration in the central nervous system. MS is the second major cause of disability following trauma, and is mostly seen between the ages of 20 - 40 years and in women. Autoimmune hepatitis (AH) is a chronic disease characterized by hypergammaglobulinemia, high levels of transaminases, pr...

Cytomegalovirus (CMV) is considered to play a role in triggering autoimmune hepatitis (AIH). It is difficult to diagnose autoimmune hepatitis because its presentation can be acute, severe, asymptomatic or chronic. Diagnosis requires multiple findings and exclusions of similar diseases. When excluding, viral etiologies are part of the differential, which in this case is CMV. If a trigger is requ...

• Vol 10 • May 2008 390 Autoimmune hepatitis is a chronic hepatitis of unknown etiology characterized by hyperglobulinemia, circulating antibodies and piecemeal necrosis on liver histology. There are only sporadic reports describing an association between autoimmune hepatitis and herbal medications [1]. Herbal remedies are among the most popular form of complementary treatments and are being ma...

One of the rarest autoimmune diseases is polyglandular syndrome type 1 which caused by defects in AIRE gene leading to affection several endocrine glands. Two out three criteria are needed for diagnosis including hypoparathyroidism, adrenal insufficiency along with other non-endocrinal symptoms such as mucocutaneous candidiasis. Management condition multidisciplinary regular long-life follow-up...

OBJECTIVE Celiac disease is an autoimmune disorder in which the risk of autoimmune liver disease is high. Autoimmune hepatitis is a chronic and progressive entity and the risk of its being associated with other autoimmune disorders such as celiac disease is high also. The aim of this study was to determine the prevalence of celiac disease in patients with autoimmune hepatitis and vice versa. ...

OBJECTIVE To investigate the association between HLA class II alleles and autoimmune hepatitis (AIH) type I in Thai patients. MATERIAL AND METHOD The clinical data of 50 autoimmune hepatitis patients type I (AIH) at Siriraj hepatitis clinic were analysed, 37 of whom were tested for HLA class II genotyping using polymerase chain reaction and sequence-specific oligonucleotide technique (PCR-SSO...