نتایج جستجو برای: b16f10 melanoma cells

تعداد نتایج: 1420217  

Journal: :Journal of immunology 2013
Jason R Baird Katelyn T Byrne Patrick H Lizotte Seiko Toraya-Brown Uciane K Scarlett Matthew P Alexander Mee Rie Sheen Barbara A Fox David J Bzik Marcus Bosenberg David W Mullins Mary Jo Turk Steven Fiering

Immune recognition of tumors can limit cancer development, but antitumor immune responses are often blocked by tumor-mediated immunosuppression. Because microbes or microbial constituents are powerful adjuvants to stimulate immune responses, we evaluated whether intratumoral administration of a highly immunogenic but attenuated parasite could induce rejection of an established poorly immunogeni...

2016
Lorena Lobos-González Verónica Silva Mariela Araya Franko Restovic Javiera Echenique Luciana Oliveira-Cruz Christopher Fitzpatrick Macarena Briones Jaime Villegas Claudio Villota Soledad Vidaurre Vincenzo Borgna Miguel Socias Sebastián Valenzuela Constanza Lopez Teresa Socias Manuel Varas Jorge Díaz Luis O. Burzio Verónica A. Burzio

We reported that knockdown of the antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptotic death of several human tumor cell lines, but not normal cells, suggesting this approach for selective therapy against different types of cancer. In order to translate these results to a preclinical scenario, we characterized the murine noncoding mitochondrial RNAs (ncmtRNAs) and performed in ...

Journal: :Molecules 2015
Grace Anne A Dória Anderson R Santos Leonardo S Bittencourt Rafael C Bortolin Paula P Menezes Bruno S Vasconcelos Rebeca O Souza Maria José V Fonseca Alan Diego C Santos Shanmugam Saravanan Francilene A Silva Daniel P Gelain José Cláudio F Moreira Ana Paula N Prata Lucindo J Quintans-Júnior Adriano A S Araújo

Remirea maritima is a tropical plant with a reticulated root system belonging to the family Cyperaceae, also known to have biologically active secondary metabolites. However, very few data on R. maritima's biological actions are available and there are no reports regarding the redox-active profile of this plant. In this study, we examined the total phenolic content of Remirea maritima hydroalco...

2010
Danielle B Rodrigues Roger Chammas Natália V Malavasi Patrícia LN da Costa Rosa M Chura-Chambi Keli N Balduino Ligia Morganti

BACKGROUND Theracyte is a polytetrafluoroethylene membrane macroencapsulation system designed to induce neovascularization at the tissue interface, protecting the cells from host's immune rejection, thereby circumventing the problem of limited half-life and variation in circulating levels. Endostatin is a potent inhibitor of angiogenesis and tumor growth. Continuous delivery of endostatin impro...

2015
Yu-Wei Lai Shih-Wei Wang Chien-Hsin Chang Shih-Chia Liu Yu-Jen Chen Chih-Wen Chi Li-Pin Chiu Shiou-Sheng Chen Allen W. Chiu Ching-Hu Chung

BACKGROUND Melanoma is an aggressive skin cancer and a predominant cause of skin cancer-related deaths. A previous study has demonstrated the ability of butein to inhibit tumor proliferation and invasion. However, the anti-metastatic mechanisms and in vivo effects of butein have not been fully elucidated. METHODS MTT cell viability assays were used to evaluate the antitumor effects of butein ...

Journal: :Cancer research 1992
M L Nierodzik F Kajumo S Karpatkin

Seven different tumor cell lines (human melanoma SK MEL 28; hamster melanoma HM29; murine melanomas B16F10 and amelanotic melanoma B16a; human colon carcinoma HCT8; murine colon carcinoma CT26; and murine Lewis lung carcinoma) were treated with thrombin at 0.5-1 unit/ml and examined for their ability to bind to adherent platelets; HM29 was studied for its ability to bind to fibronectin and von ...

2006
Mary Lynn R. Nierodzik Francis Kajumo Simon Karpatkin

Seven different tumor cell lines (human melanoma SK MEL 28; hamster melanoma HM29; murine melanomas B16F10 and amelanotic melanoma B16a; human colon carcinoma 11("IX:murine colon carcinoma CT26; and murine Lewis lung carcinoma) were treated with thrombin at 0.5-1 unit/ml and examined for their ability to bind to adherent platelets; HM29 was studied for its ability to bind to fibronectin and von...

Journal: :Cancer detection and prevention 2003
Wanzhou Zhao Frank Entschladen Hongyan Liu Bernd Niggemann Qicheng Fang Kurt S Zaenker Rui Han

The aim of the study was to investigate the antitumor and/or preventive effect of BC-4, an isomeric compound isolated from the plant Boswellia carteri Birdw. containing alpha- and beta-boswellic acid acetate in 1:1, MW 498.3. We used the MTT (3-(4,5-dimethylthiazol-2-yl) 2,5-diphenyltetrazolium bromide) assay to study the growth inhibition activity of BC-4. Tumor cells migration within a three-...

Journal: :Biological & pharmaceutical bulletin 2001
T Nagao F Abe H Okabe

The constituents of the leaves of Clerodendron bungei STEUD. (Verbenaceae) and leaves and bark of C. trichotomum THUNB. were investigated guided by the antiproliferative activity against three tumor cell lines (MK-1: human gastric adenocarcinoma, HeLa: human uterus carcinoma, and B16F10: murine melanoma). Two phenylethanoid glycoside caffeic acid esters, acteoside and isoacteoside, were isolate...

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