Economics has been a most puzzling science, namely since the neoclassical revolution defined the legitimate procedures for theorisation and quantification. Its epistemology has based on farce: decisive tests are not applied on dare predictions. As a consequence, estimation has finally been replaced by simulation, and empirical tests have been substituted by non-disciplined exercises of comparis...

The role of T lymphocytes in the control of chronic myeloid leukemia (CML) after bone marrow transplantations has been clearly shown. This effect closely correlates with graft-versus-host disease (GVHD). A specific graft-versus-leukemia (GVL) effect separate from GVHD has been postulated but has been difficult to show. One possible target for specific GVL activity is the bcr-abl fusion protein ...

OBJECTIVE Takayasu arteritis (TA) is an uncommon disease with clinical heterogeneity across different ethnic groups. We aimed to evaluate the epidemiological, clinical, and immuno-genetic features of TA in Greece. METHODS Demographic, clinical, laboratory, angiographic, and therapeutic data of 42 patients from 4 large referral centers were retrieved. Serology and Human Lymphocyte Antigen (HLA...

Metabotropic glutamate receptors (mGluRs) modulate neuronal function via different transduction mechanisms that are either dependent or independent on G-protein function. Here we investigated, using whole cell patch-clamp recordings in combination with fluorimetric measurements of intracellular calcium concentration ([Ca(2+)](i)), the metabolic pathways involved in the responses induced by grou...

Previous studies in mice and humans models have suggested an important role for CD8+ T cells in host defense to Mycobacterium tuberculosis (Mtb). In humans, CD8+ Mtb-reactive T cells have been described that are HLA-A2-, B52-, as well as CD1-restricted. Recently, we have described Mtb-specific CD8+ T cells that are neither HLA-A-, B-, or C- nor group 1 CD1-restricted. At present, little is know...

The exact process of the human brain and mind information development is still, in many ways, a true mystery. Nonetheless, it seems clear that evolutionary enabled to progress from most basic instinctive aspects evermore advanced levels abstraction, which permitted generation increasingly complex abilities elaborate language. But, how do we believe works? How are able acquire knowledge transmit...

Correlations between concentrations of cell wall components (CWCs) in the leaf sheath and stalk and resistance to stalk tunneling by the European corn borer (ECB) [Ostrinia nubilalis (Hübner)] have been reported in some maize (Zea mays L.) populations. Evaluations of resistance to ECB stalk tunneling (ECB-ST) and concentrations of neutral detergent fi ber (NDF), acid detergent fi ber (ADF), and...