We report a rare case of an elderly gentleman presenting with hemoptysis and stridor secondary to a primary tracheal EpithelioidAngiosarcoma (EAS). EAS continues to be a rare clinical entity with its occurrence in the trachea having been described only twice before to our knowledge. This case also demonstrates the importance of Immunochemistry in accurately making a diagnosis of EAS as the epit...

Burnet and Stone (1947) described a mucinsplitting enzyme in cultures of Vibrio comma which causes desquamation of the intestinal mucosa of guinea pigs and have suggested a role for this mucinase in the pathogenesis of Asiatic cholera. While possession of this enzyme may be an important factor in determining the virulence of cholera strains, it is by no means the only attribute, since avirulent...

•Vulvar angiosarcoma in a patient with pelvic radiation and chronic lymphedema•Epithelioid histologic staining positive for vimentin, ERG, CD31•Gross appearance of violaceous hyperpigmentation of the mons pubis.

To assess the utility of a single stain for both mast cell count and bacillary index (BI), 50 skin-biopsie patients were stained with Fite-Faraco (FF) stain, viewed under oil immersion and BI calculated using the Ridley's logarithmic scale, and mast cells counted as the number of cells per mm2. Mean mast cell count per mm2 at the tuberculoid pole was lowest in TT 7.9 and highest in BT 14.23. At...

Gram-negative bacillary meningitis (GNBM) is commonly seen in infants and neonates. However, GNBM can cause severe meningitis in adults, although rarely. It usually occurs after central nervous system trauma and neurosurgical procedures. The immunocompromised, the elderly, or patients with chronic diseases are at high risk.1,3 Numerous antibiotics have been tried in the treatment of GNBM, but o...

Angiosarcoma of bone is an exceedingly rare primary bone malignancy that can present as an aggressive osteolytic lesion. This subset can radiologically mimic non-vascular neoplasms and impose serious challenges in reaching the correct diagnosis. Meanwhile histological diagnosis can be extremely challenging too, as the pathological features often resemble that of aneurysmal bone cysts. We presen...

Bacillary angiomatosis (BA) is an angioproliferative disease of immunocompromised patients that usually presents as vascular tumors in the skin and subcutaneous tissues. It is caused by chronic infections with either Bartonella henselae or B. quintana. Oral cavity BA is exceedingly rare and even rarer without simultaneous cutaneous disease. We report herein the case of a 51-year-old HIV-infecte...

t was the unusual appearance of Kaposi sarcoma in the skin of young homosexual males and the coexistence of pneumocystis pneumonia that led to the description of AIDS in the early 1980s. Since then protean manifestations of cutaneous disease are recognised. The presence of skin disease can sometimes be the first indicator of HIV infection. Furthermore, the appearance of some cutaneous infection...

All eukaryotic and prokaryotic cells contain rRNA which are widely conserved Sequence analysis is often used for phylogenetic classification of organisms. Despite wide conservation, sequences also have unique species specific regions. rRNA analysis has been widely applied to the field of microbiology and has greatly expanded ever since the early reports that indicated that bacterial 5S, 16S and...

New molecular biologic techniques, particularly representational difference analysis, consensus sequence-based polymerase chain reaction, and complementary DNA library screening, have led to the identification of several previously unculturable infectious agents. New agents have been found in tissues from patients with Kaposi's sarcoma, non-A, non-B hepatitis, hantavirus pulmonary syndrome, bac...