Today, we are facing the spread of antibiotic resistance in various microbial communities. Also, researchers using new methods to replace conventional treatments prevent chronic bacterial infections. Hence, used phages or contaminant particles now as an effective method treatment many infectious diseases. Several studies have suggested that use bacteriophages is treating some Therefore, present...

in the present study, the therapeutic potential of bacteriophages virulent to staphylococcus aureus associated with goat mastitis were isolated, identified and assessed. staphylococcus aureus (host or indicator bacterium) was isolated from a goat suffering from clinical mastitis. based on cultural, morphological, biochemical tests and amplification of s. aureus specific thermonuclease gene inpc...

Bacteriophage ecology has raised an increasing attention over the past few years, thanks to improvement and contributions of microscopy, comparative genomics viral metagenomics methods. Fermented foods host dense diverse microbial communities and, therefore, represent ideal biotope for bacteriophages. If their occurrence in such environments been demonstrated decades ago, data highlighting impa...

Abstract Background Antibiotic-resistant bacteria have emerged as a serious problem; bacteriophages have, therefore, been proposed therapeutic alternative to antibiotics. Several authorities, such pharmacopeia, FDA, confirmed their safety, and some are commercially available worldwide. The demand for is expected increase exponentially in the future; hence, there an urgent need mass-produce econ...

The packaging of double-stranded DNA into bacteriophages leads to the arrangement of the genetic material into highly-packed and ordered structures. Although modern experimental techniques reveal the most probable location of DNA inside viral capsids, the individual conformations of DNA are yet to be determined. In the current study we present the results of molecular dynamics simulations of th...

Fecal microbiota transplantation (FMT) has received increased attention as a therapy for correcting intestinal dysbiosis and restoring a state of health in patients suffering from either recalcitrant infection by Clostridium difficile or more complex disease states, such as inflammatory bowel disease (IBD). The "gut microbial organ" from the donor that is used in these transplants may serve to ...

From the abyss of the ocean to the human gut, bacterial viruses (or bacteriophages) have colonized all ecosystems of the planet earth and evolved in sync with their bacterial hosts. Over 95% of bacteriophages have a tail that varies greatly in length and complexity. The tail complex interrupts the icosahedral capsid symmetry and provides both an entry for viral genome-packaging during replicati...

We isolated bacteriophages active against Propionibacterium freudenreichii from 16 of 32 swiss cheese samples. Bacteriophage concentrations ranged from 14 to 7 x 10(5) PFU/g, depending on the sample and the sensitive strain used for detection. Only a few strains, 8 of the 44 strains of P. freudenreichii in our collection, were sensitive. We observed that multiplication of bacteriophages occurre...

The aerobic granular sludge (AGS) process is an effective wastewater treatment technology for organic matter and nutrient removal that has been introduced in the market rapidly. Until now, limited information available on AGS regarding of bacterial viral pathogenic organisms present sewage. This study focussed determining relation between reactor operational conditions (plug flow feeding, turbu...