Basal cell carcinoma (BCC) is a low-grade malignancy of basal keratinocytes, the cells responsible for epidermis formation. Melanocytes are seen between the keratinocytes, but they are not responsible for this tumor type. The etiology is multifactorial, related to ultraviolet sun exposure, radiation, and immunosuppression, among other factors. This is one of the most common cancers in humans. T...

N Engl J Med 2005;353:2262-9. Copyright © 2005 Massachusetts Medical Society. ccording to the american cancer society, skin cancer is the most common cancer, accounting for about half of all cancers in the United States. More than 1 million cases of skin cancer will be diagnosed in the United States this year. 1 Basal-cell carcinomas constitute approximately 80 percent of all nonmelanoma skin c...

OBJECTIVE The purpose of this study is to review our series of metastatic basal cell carcinomas of the head and neck. STUDY DESIGN A retrospective review was conducted for this study. METHODS All cases of documented metastatic basal cell carcinomas arising from a primary within the head and neck region and presenting for treatment to one of the authors (Y.D.) were included in this review. ...

Basal Cell Carcinoma (BCC) is the most common malignant tumour of the skin. It is also the most common cancer in humans in some countries. BCC is malignant neoplasm derived from nonkeratinizing cells originating in the basal layer of the epidermis. The histology of the tumour and the surrounding stroma is characteristic. Basal cell carcinoma was first described in 1824 by Jacob who called it "u...

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